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Biomedical subjects

D Barrut

Publications and source records attributed to D Barrut.

24 records · Page 2Linked to original sources
PubMed1983

[Pseudopurpuric palmar localizations of herpetiform dermatitis].

We report an unusual manifestation of dermatitis herpetiformis in four patients. Three of them fulfill all the criteria for dermatitis herpetiformis: micro-abscesses of polymorphs in the upper papillary dermis, granular IgA deposit on IF examination, gluten-sensitive enteropathy, HLA B8. These peculiar lesions occur on palms and fingers, and appear as a petechial and ecchymotic purpura. A light painful sensation may precede the eruption. In two cases the palmar localisation initiated the course of the disease and remained isolated for more than one year. In only two cases, typical inflammatory lesions were associated on the palms. No lesions occurred on the soles. These peculiar palmar purpura-like lesions cleared with gluten-free diet or Dapsone therapy in the four patients.

Adolescent↗
PubMed1982

[O'Brien's actinic granuloma, Three cases (author's transl)].

We report three cases of 54, 58 and 65-year-old patients presenting annular lesions with centrifugal migratory extension. They occur exclusively on sun-exposed areas. In two cases, the lesions were multiple. In the third case, the lesion was single and mimicked an erythema annulare centrifugum. The past history ranged from 18 months to 8 years. Microscopic examination of the central part showed a disappearance of elastic fibers in upper reticular dermis. Examination of the ring showed in upper reticular dermis an histiocytic granulomatous infiltration with many giant cells, lymphocytes and patterns of elastic fibers phagocytosis. Similar features were found by electronmicroscopy. These three cases illustrate the typical features of O'Brien's actinic granuloma. Relationship between this actinic granuloma and granuloma annulare occurring on sun-exposed areas on one side, and necrobiosis lipoidica, Miescher's granuloma and granuloma multiforme on the other side, are discussed. On the basis of some clinical and histological patterns, the autonomy of O'Brien's actinic granuloma appears to be established.

Aged↗
PubMed1980

[Pityriasis lichenoides (author's transl)].

A review of the literature concerning the pityriasis lichenoides and the study of 34 personal cases show that three main clinical patterns are found in pityriasis lichenoides: maculo-papular, leukomelanodermal, necrotic. The course is very variable: rarely seven weeks, more often seven months and sometimes seven years. The disease is issued from an angiitis including a mostly lymphocytic infiltration. The epidermis is secondarily invaded by inflammatory cells and shows focal parakeratosis. There is no specific immunologic disorder: immunohistopathologic study is generally normal (rarely IgM or C3 deposits); no circulating immune complex is found. Some patients improved with dapsone or photochemotherapy.

Fluorescent Antibody Technique↗