Biomedical subjects

D Beker

Publications and source records attributed to D Beker.

4 recordsLinked to original sources

PubMed1992

[Serum selenium level as a diagnostic parameter in breast cancer].

The level of selenium in blood serum was determined in 33 patients with breast cancer, 13 women with verified mastopathy, and 43 healthy subjects from the Zagreb area. In the second and third quartiles the values of selenium obtained from sick subjects (41-58 micrograms/l) and healthy subjects (73-89 micrograms/l) differed significantly (p less than 0.001). In the group of subjects with mastopathy, serum selenium in the same way ranged from 67-70 micrograms/l and did not differ significantly from the group of healthy women, but differed significantly from the patients with breast cancer (p less than 0.001). Such a result leads to the conclusion that determination of selenium in the blood could be used as a noninvasive diagnostic parameter in clinical assessment of malignant breast disease.

Adenocarcinoma↗

PubMed1991

Fast determination of ochratoxin A in serum by liquid chromatography: comparison with enzymic spectrofluorimetric method.

A rapid high-performance liquid chromatographic method for the determination of low concentrations of ochratoxin A in serum is described. The extraction procedure was simple and short, and liquid chromatographic analysis was carried out isocratically on a reversed-phase C18 column, with methanol-water-acetic acid (30:70:1) as mobile phase and fluorescence detection (excitation at 336 nm, emission at 465 nm). The examined concentration range, 5-50 ng/ml ochratoxin, the recovery method was 87-94%, compared with 62-67% for the enzymic spectrofluorimetric method. The high-performance liquid chromatographic method was faster because the extraction procedure was shorter, and more sensitive so that small sample volumes could be used.

Animals↗

PubMed1990

Selenium in serum as a possible parameter for assessment of breast disease.

The level of selenium in blood serum was determined in 33 patients with breast cancer, 13 women with verified mastopathy, and 43 healthy subjects from the Zagreb area. In the second and third quartiles the values of selenium obtained from sick subjects (41-58 micrograms/L) and healthy subjects (73-89 micrograms/L) differed significantly (P less than 0.001). In the group of subjects with mastopathy, serum selenium in the same way ranged from 67-76 micrograms/L and did not differ significantly from the group of healthy women, but differed significantly from the patients with breast cancer (P less than 0.001). Such a result leads to the conclusion that determination of selenium in the blood could be used as a non-invasive diagnostic parameter in clinical assessment of malignant breast disease.

Adenocarcinoma↗

PubMedDate not supplied

A contribution to the world selenium map.

Atomic absorption spectrophotometric method was used to determine the serum selenium levels of 86 healthy individuals. Variations in age, sex, and geographically different urban regions of Yugoslavia were investigated. A group of 63 healthy children, ages 8-15 yr, were examined. Mean +/- standard deviation of the serum selenium concentration was 57 +/- 9 micrograms/L; age and geographic area had no effect on the Se status of children, but the difference between boys and girls was significant (P less than 0.05). A group of 23 men from Zagreb, ages 22-37 yr, were examined. The group was divided into three age subgroups and no difference was found among these groups. The mean Se concentration was 69 +/- 18 micrograms/L, and a statistically significant difference was found only between the group of adults and the group of children (P less than 0.05).

Adolescent↗