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D Blasko

Publications and source records attributed to D Blasko.

8 recordsLinked to original sources

[Cerebral circulation using transcranial and extracranial doppler ultrasonography in a patient with vertigo and ischemia in the area of the brain stem].

The authors examined 32 patients with vertigo, 17 patients with focal ischaemia of the brain stem and 24 patients without signs of affections of the central nervous system by transcranial and extracranial Doppler ultrasonography. They measured the flow velocity in the basilar artery (BA), in the intracranial portion of the vertebral artery (VA) and in the extracranial portion of the internal carotid artery (ICA). In patients with vertigo they investigated functional and organic changes in the area of the cervical spine. They found significant differences in the flow velocities between groups as well as in different indices calculated from the assessed values. The lowest flow velocities were recorded in patients with focal ischaemia of the brain stem. The authors evaluate the influence of haemodynamics and disease of the cervical spine on the development of vertigo.

Adult

[Changes in circulation of the blood in cerebral arteries in relation to age].

The authors examined 12 people under 40 years and 12 above 40 years, mostly healthy volunteers. They investigated the rate of blood flow in the median cerebral artery after compression of the homolateral and contralateral internal carotid. They found that in more advanced age the rate of flow in the mentioned arteries is significantly reduced. During compression tests in more advanced age the decline in the flow rate is more marked in the median cerebral artery on the side of compression. In the other arteries the flow is promoted but the age dependence is not marked. The authors conclude from these findings that with advancing age the possibilities of autoregulation deteriorate more than those of the collateral circulation via Willis' circle.

Adult

Effect of chronic ethanol treatment and subsequent ischaemia on phospholipids and cholesterol in the rabbit spinal cord.

Rabbits received ethanol p.o. (0.96 g. ml-1, 2.88 g.kg-1) for 30 days. Ischaemia was induced by abdominal aorta ligation for 40 min in animals with or without ethanol treatment. The content of total (TPL) and individual phospholipids, i.e. ethanolamine (PE), choline (PC), serine (PS), phospholipids and sphingomyelin (SM), as well as unesterified cholesterol (UC) was determined in the gracilis fascicle (Fg), and the dorsal (Dp) and ventral (Vp) part of the lumbar and cervical spinal cord. Chronic ethanol treatment resulted in a statistically significant decrease in the PE content in Dp of cervical spinal cord. Cholesterol content was increased in all parts of the spinal cord studied (increased UC/TPL molar ratio). Ischaemia of the spinal cord induced a significant decrease in PI. In ethanolic animals ischaemia decreased the PS content in Dp and Vp of ischaemized lumbar spinal cord. The combined effect of ischaemia and chronic ethanol did not result in a cumulative pattern of changes suggesting a partially opposite influence of both stimuli on lipid metabolism as well as its altered regulation after chronic ethanol treatment in the spinal cord.

Animals