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D Blatter

Publications and source records attributed to D Blatter.

8 recordsLinked to original sources

Developing a radiology data base for quality assurance.

Radiology Information Systems (RIS) are designed to capture and manage the data associated with ordering, executing, reporting, and billing x-ray procedures. The HELP Hospital Information System contains a radiology subsystem that supports these functions. In an effort to enhance quality assurance initiatives, we have created a supplemental data base. This data base contains not only the data traditionally generated by RISs but also data from the hospital system that is relevant to quality assurance. One of the goals associated with this data base is to use techniques from the discipline of Continuous Quality Improvement (CQI) in the radiology department. A focus of our initial efforts has been the time necessary to provide x-ray reports to ordering physicians once the imaging examination has been performed. Efforts to manage the portion of this time interval caused by transcription have resulted in a substantial decrease in the time required for this function. A second goal of this project is to evaluate the quality of x-ray ordering. This objective requires a computerized record of the outcome of the x-ray procedure. Initial analysis of data derived from this data base indicates significant differences in the ordering behavior for computed tomography (CT) examinations among a test group of physicians. A third goal is to do quality assurance on x-ray reports. Experience with pilot systems has shown promising results using a mathematical model of report quality. We hope to leverage these techniques and this quality assurance data base to define a COI process for medical reports in general and for x-ray reports in particular.

Database Management Systems↗

Corpus striatum and traumatic brain injury.

The possibility of a 'subcortical' syndrome differentially affecting memory in traumatic brain injury (TBI) subjects was examined. Magnetic resonance imaging scans of 46 traumatic brain injured male patients were compared with those of 34 male control subjects. Surface area measurements of the corpus striatum were calculated for both groups. Results demonstrated no significant differences in corpus striatum surface area measurements. Additionally, TBI patients were grouped according to severity of injury, as well as degree of corpus striatum atrophy, and neuropsychological outcome was examined. There were modest (r = 0.35) but significant correlations between corpus striatum degeneration and the delayed recall trial and total score of the Rey Auditory Verbal Learning Test, but no other correlations between neuropsychological and corpus striatal surface area were significant. Because subcortical pathology may have a differential effect on memory, recognition and recall memory were further analysed, but no significant differences were found. TBI subjects with the smallest corpus striatum values did not test significantly different from TBI patients with normal corpus striatum values or differences in cortical atrophy, as determined by a ventricle-to-brain ratio. These findings suggest that there is not a unique pattern of subcortical pathology involving the corpus striatum in TBI.

Adolescent↗

Day of injury CT scan as an index to pre-injury brain morphology.

This study compared the ventricle-to-brain ratio (VBR) of the day-of-injury (DOI) computerized tomogram (CT) in traumatic brain-injured (TBI) patients with post-injury (2 months or greater) magnetic resonance (MR) VBRs in the same patients and in medical control subjects. The DOI VBR did not differ significantly from the medical controls, but both (DOI and medical control VBR) differed significantly from post-injury VBR. Additionally, a case study is presented wherein MR imaging studies were obtained prior to TBI so that a direct comparison of pre-injury to DOI to post-injury changes could be made. In this case the pre-injury and DOI VBRs were within approximately 9% of each other. In contrast, the post-injury VBR demonstrated over a 100% increase in comparison to either the pre-injury or DOI scan. This case and another case are illustrated using three-dimensional image analysis to represent ventricular change over time. These cases, along with the similarity of the DOI VBR with the medical controls, suggests that the DOI VBR can be utilized as an estimate or index of pre-injury ventricle/brain morphology. This will permit the use of DOI CT data for within-subject designs in TBI research that examines the course of degenerative changes over time.

Adolescent↗

Fornix degeneration and memory in traumatic brain injury.

Fornix-to-brain ratios (FBR) based on postinjury magnetic resonance (MR) studies were calculated on a group of 27 female traumatic brain injury (TBI) patients and 18 female medical controls by taking the widest aspect of the fornix at the level of the anterior horns and third ventricle and determining a fornix surface area. The FBR was significantly reduced in the TBI group (FBR = 0.1121) as compared to the normal control group (FBR = 0.1766). Despite these significant FBR findings indicating prominent atrophic changes of the fornix in TBI patients, the FBR did not relate systematically to neuropsychological outcome. These findings clearly indicate fornix vulnerability in TBI and that current quantitative MR methods are sensitive enough to detect such changes. However, fornix degeneration constitutes only one of many contributing factors to the anatomic basis of TBI-induced cognitive disturbances, as fornix atrophy did not relate systematically to neuropsychological outcome.

Adolescent↗

Degenerative changes in traumatic brain injury: post-injury magnetic resonance identified ventricular expansion compared to pre-injury levels.

Magnetic resonance (MR) scans obtained 42 days and 10 months post-injury were compared to scans obtained in similar planes three months prior to injury. In comparison to pre-injury scans, post-injury MR scan analysis demonstrated significant ventricular volume increase which is considered a measure of the degree of diffuse axonal injury. Most important, the trauma induced degenerative effects appeared to be quite complete by 42 days post-injury as there was little further degeneration that occurred between the 6 week and 10 month post-injury scans. This study demonstrates that in humans the majority of gross trauma-induced degenerative changes are complete by 6 weeks post-trauma.

Adult↗

Magnetic resonance identified ventricular dilation in traumatic brain injury: comparison of pre- and postin jury scan and postin jury results.

A case study is presented in which a patient received magnetic resonance (MR) imaging of the brain 3 months prior to a severe traumatic brain injury (TBI). The post-TBI MR findings are compared and contrasted with the pre-TBI MR images. The posttraumatic changes demonstrate a significant dilation of the ventricular system which reflects diffuse axonal injury and loss of brain substance. Correspondingly, the neuropsychological studies in this individual reflect global deficits which match the nonspecific, traumatically induced degenerative changes found in the postinjury MR scan. This case study is unique in that specific preinjury MR findings are available for direct comparison and quantitative analysis of TBI-associated changes in brain structure with neuropsychological outcome.

Clinical Conference↗

Day-of-injury CT as an index to pre-injury brain morphology: degree of post-injury degenerative changes identified by CT and MR neuroimaging.

A detailed case study is presented in which pre-injury CT scan findings are compared and contrasted with post-injury CT and MR results in a case of traumatic brain injury (TBI). The day-of-injury scan represented an adequate estimate of pre-injury morphological status based on cross-sectional area measurements of the ventricular system. By comparing pre-injury CT measurements with those obtained on the day of injury, 2 days post-injury and 16 months post-injury via assessing cross-sectional area of select ventricular regions (e.g. anterior and temporal horns, body and third ventricle) it was demonstrated that the TBI induced over a 50% ventricular expansion. Such ventricular expansions are felt to provide some index into diffuse axonal injury which may provide a means of eventually quantifying the degree of structural damage secondary to TBI. This analysis also demonstrated that there were no significant differences between selected cross-sectional ventricular areas in the 15 day and 16 month post-injury MR scans. This finding suggests that the degenerative effects of TBI have a rapid onset and are becoming readily apparent by 15 days post-injury. Thus, early imaging may provide a good index of long-term morphological outcome in TBI.

Adolescent↗