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D Bordin

Publications and source records attributed to D Bordin.

4 recordsLinked to original sources

Effect of middle-intensity exercise on carnitine and beta-hydroxybutyrate plasmatic concentration in men and women.

The purpose of this study is to describe the dynamics of carnitine, its esters and beta-hydroxybutyrate, during a prolonged moderate-intensity physical exercise, as the literature data (Angelini 1986, Carlin 1986, Lennon 1984) up to date reported were not uniform. In our study twenty-two untrained subjects (11 males, 11 females) performed a test exercise on a motor-driven treadmill for 90 min at 50-60% of VO2 max. Blood samples were obtained at rest, at 20, 40, 60 and 90 min during the exercise and after 30 min of recovery. Men show an increase over rest values in short chain acyl carnitine after 90 min of exercise higher than women (M 157%, F 80%), while women have a more elevated relative increase in beta-hydroxybutyrate (M 201%, F 233%); Total carnitine in both sexes is not significantly modified.

3-Hydroxybutyric Acid

Gonadotropin decrease induced by prolonged exercise at about 55% of the VO2max in different phases of the menstrual cycle.

In order to evaluate the influence of physical exercise on the hypothalamic-pituitary-ovarian axis, we studied ten women in the early follicular phase (EFP), twelve in the late follicular phase (LEP) and nine in the luteal phase (LP). The test consisted of a 90-minute physical exercise on a motor driven treadmill at 55-60% of VO2max. Blood samples were taken before, during and after the test. Prolactin and cortisol did not increase in any phase. Estradiol showed a significant increase in LFP (from 361.5 +/- 110.6 to 472.7 +/- 138.9 pmol/L) and in LP (from 457.2 +/- 94.6 to 555.3 +/- 96.9 pmol/L) but not in EFP. Progesterone levels increased significantly only in LP (from 28.2 +/- 6.7 to 33.5 +/- 6.7 mmol/L): Luteinizing hormone (LH) levels decreased significantly in all phases: from 13.7 +/- 2.0 to 10.5 +/- 1.1 IU/L in EFP; from 14.6 +/- 2.1 to 11.5 +/- 1.9 IU/L in LFP and from 7.5 +/- 1.3 to 5.7 +/- 1.0 IU/L in LP, while follicle stimulating hormone (FSH) levels decreased only in LFP (from 8.1 +/- 0.5 to 6.7 +/- 0.6 IU/L). Our exercise protocol (prolonged, continuous and moderate) was able to cause a decrease in gonadotropins levels, and this phenomenon is not due to changes in the other tested hormones.

Adult

[Avoidance learning in rats treated with estrogens].

Male and female rats were treated with estradiol benzoate in the 5 degrees day of life. The avoidance conditioning, tested after 65 days, was significatively impaired in males treated with estradiol, a significative retardation was observed in females treated, but no significant end-difference versus no-treated females. It is supposed that a hormone induced synaptic shaft/spines ratio in preoptic area may be involved in avoidance conditioning.

Amygdala