Biomedical subjects
Publications and source records attributed to D Briones-Carrillo.
A modification of the antiblastogram, a technique originally used for predictive anti-cancer drug testing, is employed in this work to select microorganisms producing antineoplastic antibiotics.
The antiblastogram allows the specific determination within a few days of the effect of single and combined chemotherapeutic agents upon the cells of a given tumor, informing about their action, summation, antagonism and synergism. It permits to evaluate the activity of both hydrosoluble and liposoluble products, giving information about the possible activation or inactivation of chemotherapeutic agents by different substances and subcellular fractions.