Biomedical subjects

D Brkić

Publications and source records attributed to D Brkić.

17 recordsLinked to original sources

PubMed2002

Activity of essential oils of three Micromeria species (Lamiaceae) against micromycetes and bacteria.

The chemical composition of essential oils from three Micromeria species: M. dalmatica Benth., M. albanica (Griceb. ex K. Mal) Silić and M. thymifolia (Scop.) Fritsch were investigated by GC and GC-MS and their antibacterial and antifungal activities against seven fungal and six bacterial species were evaluated. Biological assays showed strong fungitoxicity of oils from all three Micromeria spp., particularly M. albanica, against all fungi tested. Essential oils of these species also exerted antibacterial effect against Streptococcus aureus, Escherichia coli, Bacillus subtilis and Micrococcus luteus at low concentrations. Higher concentrations of essential oil of M. albanica and M. dalmatica were active against Gram-negative Pseudomonas aeruginosa, which could be due to the high content of piperitenone oxide.

Anti-Bacterial Agents↗

PubMed1992

[Hemorheologic changes in patients with essential hypertension treated with prazosin].

Prazosin which is a selective alfa-1 blocking drug has a very good antihypertensive effect. Its hemorheological effects were studied in 20 patients with essential hypertension (I and II degree according to WHO classification). After 6 weeks of the therapy with prazosin, hematocrit and viscosity of the whole blood and plasma were significantly reduced, because of hemodilution, while aggregability of erythrocyte and "Tk" values were not significantly reduced. Platelet aggregation induced by collagen, ADP and adrenaline, showed a decrease after the treatment. Assuming the hemorheological effects not to be crucial in choosing an antihypertensive agent, we must not, however, neglect them, especially in patients with compromised hemorheological profile, and we should take advantage of the positive hemorheological effect of prazosin, particularly in a long antihypertensive treatment.

Adolescent↗

PubMed1990

[Factors which affect patient cooperation in the therapy of hypertension].

The socio-demographic factors (sex, age, social status and professional qualification), side effects of antihypertensive drugs and the therapeutic effects were compared with patient compliance in a group of 387 hypertensive patients. The results showed that the sociodemographic factors and presence of side effects had no significant influence upon patient compliance. Unlike these factors, therapeutic effects had a significant impact upon patient compliance.

Adult↗

PubMed1968