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Biomedical subjects

D Bryden

Publications and source records attributed to D Bryden.

9 recordsLinked to original sources

Some laboratory correlates of drinking habits.

The effect of drinking habits on the frequency distributions of eight biochemical or haematological test results was studied in 7915 patients attending a multiphasic health testing centre. Increasing incidences of abnormal results with increasing alcohol intake, at levels of alcohol intake habitual for a large proportion of the population, were found for plasma gamma-glutamyl transpeptidase, triglycerides and uric acid, and for erythrocyte mean corpuscular volume. Of four frequently used liver function tests, aspartate aminotransferase, alkaline phosphatase, bilirubin, and albumin, only aspartate aminotransferase was strongly affected by drinking habits. These findings have relevance for the detection of individuals whose drinking habits are harmful to them, and for the interpretation of 'profile' results.

Alcohol Drinking↗

Estimation of alcohol intake from laboratory results.

Subjects with abnormalities in a number of laboratory tests were shown to have higher than usual probabilities of being heavy drinkers. Quantitative estimates have been made of the probabilities of heavy drinking from the results of the following tests: gamma-glutamyl transpeptidase, mean corpuscular volume, uric acid, triglyceride, and aspartate aminotransferase. In men, but not in women, there was a clear increase in this probability with increasing test results for these five tests, which may prove useful in the detection of individuals who are at risk from their drinking habits.

Alcohol Drinking↗

Drinking and drug taking patterns of 8,516 adults in Sydney.

Data on the drinking and drug taking patterns of 8,516 adults who had been through a Medicheck screening were analysed. This is the largest sample studied in Australia to date. The alcohol intake pattern of at least 29% of males and 9% of females puts them "at risk" of physical and/or psychosocial complications; 11% of males and 2% of females were considered to be at high risk. Very few heavy drinkers considered themselves to have a drinking problem and even fewer had been told by their doctor that they were problem drinkers. One-quarter of all the women took either psychotropic drugs or analgesics regularly; 19% of females, compared with 7% of males, took one or more of the psychotropic drugs (mainly tranquillizers) regularly, and 9% of females compared with 3% of males took analgesics regularly. Approximately one-third of both males and females were current smokers, but more males than females had given up smoking. The important role to be played by general practioners in the prevention and early treatment of drug dependence is highlighted by these findings.

Adult↗