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Biomedical subjects

D Bullock

Publications and source records attributed to D Bullock.

8 recordsLinked to original sources

Reconciling stable asymmetry with recovery of function: an adaptive systems perspective on functional plasticity.

This article examines alternative ways of resolving an apparent paradox that has emerged from neuropsychological studies of language development: How can the developmentally stable functional asymmetry ("hemispheric specialization") observed in neurologically intact children be reconciled with the dramatic recovery of function often displayed following unilateral brain damage? The alternative resolutions we consider differ most critically in the roles they assign to lesion-induced neural reorganizations versus lesion-related release of preexisting functional potentials. Though arguments are given in favor of the latter as the primary factor in functional recovery, the primary goal of the article is to clarify the conceptual issues raised by recent empirical research.

Brain

A comparative trial of pivmecillinam and ampicillin in bacteriuria of pregnancy.

A comparative trial of pivmecillinam and ampicillin was performed on 100 women with bacteriuria of pregnancy. They received either 400 mg pivmecillinam four times daily or 500 mg ampicillin four times daily for seven days. Cure rates at two weeks were 88% in the pivmecillinam group and 85% in the ampicillin group. At six weeks the respective rates were 76% and 64%. Failure of therapy was not associated with the appearance of bacterial resistance in either treatment group. Side-effects, particularly vomiting and premature cessation of therapy, were significantly more frequent in the pivmecillinam group. No significant effects on liver function were found. In subsequent patients treated in a non-comparative manner with 200 mg pivmecillinam three times daily, the incidence of side effects was markedly reduced with no loss of efficacy.

Amdinocillin Pivoxil

Guidelines for family interviewing and brief therapy by the family physician.

Psychosomatic and behavioral problems are commonly seen in the practice of family medicine. If these problems are viewed as difficulties with family interaction, rather than as difficulties of an individual family member, intervention may be more successful. Treatment of families with problems involves interviewing the family unit, identifying and altering dysfunctional behavioral patterns within the family which serve to maintain the problem, and making selected referrals to experienced family therapists.

Behavior

School phobia.

Pediatricians and other primary care providers are in an ideal position to prevent, to diagnose and to treat children with school refusal. Detection requires recognition of high risk situations, and delineation of possible reality factors or environmental hazards. The physician will find school refusal associated with perceived or actual physical illness, debility, or vulnerability, family stresses including illnesses and marital problems, over-protective mother-child interaction patterns, and previous difficulties in achieving mother-child independence and separation. Confirming the diagnosis depends on interview with family members. Positive indicators are dysfunctional patterns of family communication, parental emphasis on illness, and manipulative behavior on the part of the child. Data from the school on absenteeism need to be supplemented by the school's observations of individual achievement and ability measures, grades, and teacher observations of peer and adult interaction. Treatment techniques center around returning the child to school by involving the child, the family, and the school in this process. Specific counseling techniques and principles aim to recognize each individual's feelings and to stress the active role of the parents in solving problems together. Follow-up is based upon assessment of clearly understood short-term and long-term goals. Referral should be rare, and should not be undertaken before proper evaluation has been completed. Making a referral "stick" depends greatly upon the degree of rapport and trust which has been established with the family. In most school refusal cases, management by the pediatrician or primary physician can be a rewarding, stimulating experience which provides a high degree of parent and physician satisfaction.

Adolescent