The authors have investigated in 6 dogs the disturbances of the perfusion determined by ligature of the main left pulmonary artery, of the pulmonary veins, and mixed ligatures. The scintigraphic method was used (consisting in intravenous injection of radionuclide-labelled ferric colloids, and detection with the Anger camera). In 12 dogs electrocardiographic modifications were also investigated, occuring at various intervals of time after the above-mentioned ligatures. With the aid of scintigraphy it was noted that pulmonary perfusion was abolished in the corresponding lung both immediately and at 24 hours following ligatures. With the aid of scintigraphy it was noted that pulmonary perfusion was abolished in the corresponding lung both immediately and at 24 hours following ligature of the vessels. The same aspects was noted in all three types of ligature. Consecutive infarctions were noted at necropsies. The electrocardiogram evidenced sings of coronary failure when all the pulmonary veins of one lung were ligatured, signs of ventricular and atrial overcharge in dogs with ligature of the pulmonary artery and mixed modifications, although less severe, in combined vascular ligatures. The more rapid evolution toward death of dogs with ligatures of the pulmonary veins could be explained by the coronary failure.

Animals↗

PubMedDate not supplied

[Use and evaluation of radiophotography in the ambulatory care of lung diseases].

In the methodological cabinet for pneumology of the Institute of Phtysiology, radiophotography was employed in the following fields: a) screening of acute and chronic pneumopathies as appears from : the increase in the number of cases of non-specific pneumopathies as compared with cases of tuberculosis and the quantitative contribution of the method reflected in the fact that over 80% of the cases with non-specific pneumopathies were detected by radiophotography; b) diagnosis -- by comparing with the data recorded in the files, multiple incidences (front, posterior lordosis, profile); locally pointed (targeted) photographs, rf quantified functional tests in cases suspected of C.O.B.P.: c) follow-up of the evolution of dispensary cases and of the therapeutical effect; d) scientific research and teaching activities through epidemiological and pathogenesis studies, thus allowing for a valorification of the files over a 16 years period. The use of the radiophotographic method in the activity of a cabinet of pneumology is necessary especially because it allows for an early detection, a superior morphological diagnosis, as compared with radioscopy (fluoroscopy), for an objective and economical follow-up of the cases, providing at the same time material for scientific research and teaching demonstrations.

Ambulatory Care↗

PubMedDate not supplied

[Retrospective study of the value of radiophotographic examinations in the detection of pulmonary cancer].

Out of a total of 123 cases of centro-hilar pulmonary carcinoma and of 65 cases of carcinoma with peripheral localization changes on the previous radiophotographic images were found in 54% of the cases. The time necessary for doubling of the tumour size was of 22 months for the peripheral forms of cancer. The suspicion of pulmonary cancer was mentioned in the radiophotographic register two years before the diagnosis of the disease was made.

Humans↗

PubMedDate not supplied

[Pulmonary histiocytosis X].

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Adult↗

PubMedDate not supplied

[Correlations between alpha 1-antitrypsin deficiency and some exogenous risk factors in patients with chronic obstructive bronchopneumopathy].

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Adult↗

PubMedDate not supplied

[Contribution of pulmonary scintiscanning to the diagnosis of chronic obstructive bronchopneumopathy].

In a lot of 32 cases of chronic obstructive bronchopneumopathy, a correlation was established between the extent and location of the regional perfusion deficiencies (studied by scintigraphy) and overall functional disturbances Vmax MEVS X 100VC, residual volume, R, PaO2, PaCO2). In 85% of the cases regional perfusion disturbances were detected and grouped into six scintigraphic types. A good correlation was found between these disturbances and the MEVS X 100/VC index and modified partial pressure of the gases (O2, CO2) in the arterial blood. Unexpected was the absence of a mathematical correlation between perfusion disturbances and the residual volume and R, suggesting the great variety of the disturbances grouped under the general denomination of chronic obstructive bronchopneumopathy.

Adult↗

PubMedDate not supplied

[Morphological (Macro-, micro-electronoptical) changes and cytoenzyme changes after ligation of the pulmonary artery, pulmonary veins and both in dogs].

In six dogs ligature of the main pulmonary artery was performed, and in five other ligature of the pulmonary veins was carried out, while in five other animals combined simultaneous ligatures were made. Extensive infarcization was noted, of the pulmonary tissue, with an evolution toward death, in all types of ligatures. Death occured earlier in ligatures of the pulmonary veins. All the interventions were performed on the left lung, under general anesthesia, orotracheal intubation and assisted respiration. Electron-optic investigation revealed mitochondrial alterations 30 minutes after ligature of the pulmonary veins and 2 hours after that of the pulmonary arteries. The lesions were extensive in time. In the infarction areas the activity of the energetic enzymes (SDH, NADH2, G6PD, LDM) appears to be reduced, and even completly abolished. This occurs earlier when pulmonary veins are closed. On the basis of clinical and surgical data already mentioned in the literature, as well as on that of the experimental studies performed, the authors consider that ligature of the pulmonary artery, either therapeutically or due to various necessities, an intervention that is recommended by some surgeons, is not a functional type of intervention, and can even have ill-fated results, especially if the pulmonary venous circulation is also involve in the pathological process.

Animals↗

PubMedDate not supplied

[Clinical studies of the role of the fluorescent circulating antibody test in the diagnosis of active tuberculosis].

The value was studied, of the test of circulating fluorescent antibodies against M. tuberculosis in establishing the diagnosis of active tuberculosis in 610 patients classified in 4 groups: 1. active tuberculosis bacteriologically confirmed; 2. active tuberculosis with negative bacteriological examination, but confirmed by other methods of criteria; 3. stabilized tuberculosis; 4. non-tuberculous affections. The specificity of the test in active tuberculosis was of 80% in adults and of 91,5% in children. The test was negative in 80,3% of stabilized tuberculosis cases and in 69% of non-tuberculous affections. The sensitivity was lower in active tuberculosis with positive bacilloscopy (67%) against active tuberculosis with negative bacilloscopy (90,6%), a fact explained by a high consumption of anti-bacillary antibodies, demonstrated by positivation of the test when bacilloscopy becomes negative. The use of the test is indicated in establishing a therapeutic test, and in the context of clinical and radiologic explorations, as well as in the expertising of working capacities of previous tuberculosis patients.

Age Factors↗