PubMed Health⌕ Search

Biomedical subjects

D Butković

Publications and source records attributed to D Butković.

5 recordsLinked to original sources
PubMed1990

[Ventilatory function of the lungs in patients with ankylosing spondylitis].

The ventilatory function of the lung was studied in 100 patients (85 men and 15 women) suffering from ankylosing spondylitis. The mean age of the patients was 48 years (range: 29-72) and the mean duration of the disease was 18 years (range: 4-37). In 74% of the cases there was evidence of impaired ventilatory function of the lung. Most of the affected patients exhibited restrictive ventilation disorders (57 or 77%), the incidence of restrictive-obstructive (12 or 16.2%) and obstructive ventilation disorders (5 or 6.8%) being considerably lower. While there were no significant differences in the incidence of restrictive ventilation disorders with respect to the age of the patients (t = 0.84; P greater than 0.05) and the duration of the disease (t = 0.84; P greater than 0.05), a highly significant correlation was found between the functional stage of the disease and the severity of restrictive ventilation impairment (r = 0.46; P less than 0.001).

Adult↗
PubMed1976

Respiratory response to tobacco dust exposure.

Results of a study of the respiratory responses of 318 nonsmoking female workers to long-term tobacco dust exposure are reported. The mean total tobacco dust concentrations ranged from 0.9 to 27.5 mg per m3; the respirable fraction, from 0.3 to 3.6 mg per m3. The mean length of exposure to tobacco dust was 14.9 years; 24 per cent of the workers had been exposed to tobacco dust for 20 years or more. Comparatively low prevalences of chronic respiratory symptoms were found, and only the prevalences of chest tightness and wheezing were significantly higher among workers exposed to tobacco dust than those of the control group (P less than 0.01). Calculating the expected 1-sec forced expiratory volume and forced vital capacity values by means of multiple linear regression equations, developed on the basis of data obtained in the 210 control subjects, revealed no significant differences between the measured and expected ventilatory capacity values among any of the groups of the workers observed. In contrast to negative findings with regard to chronic respiratory effects, significant acute decreases in ventilatory capacity during the work shift were recorded. No dose-response relationship was found between the level of exposure and the acute decreases in ventilatory capacity.

Adolescent↗
PubMed1975

Lung function in textile workers.

Acute changes in ventilatory function during a workshift with exposure to hemp, flax, and cotton dust were measured on Mondays in a group of 61 textile workers, all working on carding machines. In addition, single-breath diffusing capacity (DLCOSB) was measured before dust exposure on Monday in 30 of the 61 workers. Large acute reductions during dust exposure were recorded in maximum expiratory flow rate at 50% VC (MEF50%), ranging from 38 to 22%. Acute reductions of FEV1-0 were considerably smaller, ranging from 17 to 9%. There was a statistically significant increase in residual volume (RV) with very small and insignificant changes in total lung capacity (TLC). Although preshift FEV1-0 and FVC were decreased, DLCOSB was within normal limits. Plethysmographic measurements in six healthy volunteers exposed to hemp-dust extract confirmed the results obtained in textile workers, that is, that TLC does not change significantly during dust-induced airway constriction and that maximum expiratory flow rate at 50% VC (MEF50%) is a more sensitive test than FEV1-0 in detecting acute ventilatory changes caused by the dust extract.

Adult↗
PubMedDate not supplied

[Respiratory function in glass blowers].

The prevalence of chronic and acute respiratory symptoms and diseases and changes in lung function in a group of 80 glass blowers have been investigated. In addition a group of 80 not exposed workers was used as a control group for respiratory symptoms and diseases. In glass blowers, there was significant increase in prevalence of chronic bronchitis, nasal catarrh, and sinusitis than in the controls. Glass blowers exposed for more and less than 10 years had similar prevalences of respiratory symptoms. A large number of glass blowers complained of acute across-shift symptoms. Significant increase in FVC, FEF50 and FEF25 was documented at the end of the work shift. Comparison with predicted normal values showed that glass blowers had FVC and FEF25 significantly lower than predicted. RV and RV/TLC were significantly increased compared with the predicted normal values. DLCO was within the normal values in most glass blowers. It is concluded that work in the glass blower industry is likely to lead the development of chronic respiratory disorders.

Adult↗