Biomedical subjects
Publications and source records attributed to D C Abelson.
This study was undertaken to compare the pH response of enamel and cemental plaques to a sucrose rinse challenge. The plaque pH readings on the enamel surfaces were consistently lower than the subjacent cemental plaque pH readings on the same teeth at the same time intervals following the sucrose exposure.
The purpose of this work was to study the effect of chewing a sorbitol-sweetened gum on whole and parotid salivary flow rates, and on the cemental plaque pH response to a sucrose rinse challenge, in subjects with low salivary flow. The results show that chewing a flavored sugarless gum significantly increases salivary flow rates in individuals with dry mouth. Additionally, chewing the sorbitol-sweetened gum effectively prevents the fall in cemental plaque pH generally seen in response to a sucrose challenge. This indicates that chewing a sorbitol-sweetened gum provides a palliative and possibly a protective benefit for people who suffer from dry mouth.
The purpose of this study was to assess the effect of a sorbitol sweetened breath mint on salivary flow and plaque pH in subjects suffering from xerostomia. The breath mints effectively increased whole and parotid salivary flow rates during a 10-minute test period. Additionally, the mints reduced the acidogenic effect of a 10% sucrose rinse, as measured by changes in plaque pH. This change was presumably caused by the sialogogic action of the mints. The efficacy of sorbitol sweetened breath mints as a palliative, and possibly therapeutic aid for individuals with xerostomia compares favorably with the results of an earlier study similarly testing the effects of sorbitol sweetened chewing gum.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Literature concerning the relationship between denture plaque, oral pathology, and the nature and effectiveness of the products commercially available for cleaning dentures has been reviewed. The literature reports indicate that (1) plaque on the tissue surface side of the denture is unquestionably a major etiologic factor in the pathogenesis of denture stomatitis, inflammatory papillary hyperplasia, and chronic candidiasis and (2) there are shortcomings in the popular products used by the public to clean their dentures. The protocol and results of a study to test the plaque removal effectiveness of a new denture cleansing product are described. In this study, the plaque removal effectiveness of the ultrasonic device tested, when used with water alone, was found to be substantially greater than that of two popular alkaline-peroxide soak-type denture cleansers, Efferdent and Polident.
The effect of saliva on plaque acidogenesis was studied in ten caries-resistant and ten caries-susceptible subjects. Plaque pH was measured in vivo following exposure to a sucrose substrate under varying conditions of salivary access. Our findings demonstrate that when there is no salivary access, plaque pH levels are similar in the CR and CS groups. As the access to saliva is increased, the observed pH minima increased to a greater degree in the CR subjects than was noted in the CS subjects. This indicates that saliva (notably stimulated saliva) plays a major role in modifying plaque pH and quantitatively reflects caries status.
Explore the source record for details and available documents.
Eighteen patients with alcoholic cirrhosis were examined, and parotid saliva was collected. Enlargements of the parotid glands were seen in eleven of the eighteen patients (61%). This percentage is in accord with the data previously reported. The salivary findings of increased flow rate, protein, and amylase levels indicate that hypertrophy and increased acinar function may be a component of the parotid enlargement and that, furthermore, a fatty replacement of functional gland tissue is probably not involved. In addition, the salivary electrolyte changes found, increased potassium with effectively decreased sodium excretion, suggest that the elevated aldosterone level commonly found in cirrhotic patients affects salivary secretions in these patients in much the same way as it does in patients with hypertension.
Separately collected parotid and submaxillary salivary samples from 20 diabetic and 20 matched control subjects were analyzed for flow rate, electrolyte content and immunoglobulin (IgA, IgG and IgM) levels. Flow rates did not vary significantly between the two groups of subjects; calcium ion content, however, was higher in the diabetic subjects for both salivary glands. The presence of salivary IgI in 6 of 10 patients was also a significant finding. Any attempt to draw a conclusion between the severity of periodontal disease and Diabetes Mellitus from the above findings is still speculative but does indicate further areas of research.
Explore the source record for details and available documents.
The purpose of this research was to study the effect of five test hydrogenated starch hydrolysates on plaque pH in vivo. The results were compared with those produced by positive and negative controls. The results indicated that three test materials, Lycasin (Roquette Corporation, Gurnee, IL), Crystalline maltitol, and Maltisorb (Roquette Corporation, Gurnee, IL), were statistically equivalent to the negative control, sorbitol, and therefore can be considered noncariogenic.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.