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Biomedical subjects

D C Dahlin

Publications and source records attributed to D C Dahlin.

At least 73 records · Page 4Linked to original sources

Pelvic "lipolymph nodes": a consideration in the differential diagnosis of pelvic masses.

Twelve patients with pelvic "lipolymph nodes" were seen at the Mayo Clinic during a period of 26 years. Most of the patients were perimenopausal or postmenopausal, and all but one were obese. The average size of the nodes was 6.6 cm, with the range being 2 to 14 cm. The most frequently involved nodes were the external iliac and obturator groups. Excretory urography and pelvic ultrasound scan (high-resolution scanner) were helpful in determining the extraperitoneal location and the solid nature of the tumors. Lymphangiography performed in one case was helpful in confirming the nodal origin of the pelvic tumor. Exploratory laparotomy was required to determine the exact nature of the lesion in all patients. The treatment consisted of simple removal of the involved nodes. No recurrences have been observed.

Adipose Tissue↗

Chondrosarcoma: a clinicopathologic and statistical analysis.

The case histories and tissue sections from 280 patients with chondrosarcoma of the bones of the limbs, limb girdles, and spinal column were studied retrospectively, and the findings were correlated with survival by actuarial methods. One hundred thirty patients with no prior treatment who underwent curative surgery were studied separately. Size and histologic grade of tumor were the most significant prognostic factors. Control of the primary lesion was found to be of critical importance; local recurrence adversely affected survival.

Adolescent↗

A clinicopathologic study of 20 cases of large-cell (atypical) Ewing's sarcoma of bone.

A review of 347 Ewing's tumors that were seen at the Mayo Clinic during the period to the end of 1978 revealed 20 that differed histologically from the remainder. These 20--called "large-cell Ewing's tumor"--differed from the classic Ewing tumor in having larger, more pleomorphic cells, often with conspicuous nucleoli. More males than females had such tumors, and most patients were in the second decade of life. The diaphysis of long bone was commonly involved. The radiologic appearance was that of a permeative lesion. This large-cell Ewing tumor may be confused with malignant lymphoma and small-cell osteosarcoma. In the present study, there was no apparent difference in the clinical behavior of large-cell and typical Ewing's tumors.

Adolescent↗

Persistent postoperative hyperparathyroidism.

Persistent hypercalcemia after cervical exploration for suspected primary hyperparathyroidism is rare. In this retrospective review, some lessons and pitfalls have been emphasized--knowledge that should minimize this occurrence. There is no better lesson than experience. We concur with Van Vroonhoven and Muller that, in most instances, failure of the primary operation is unnecessary. This is supported by our review, in which 500 patients underwent exploration for primary hyperparathyroidism, 95 per cent of whom were rendered normocalcemic postoperatively, with minimal postoperative morbidity and an operative mortality of zero per cent.

Adenoma↗

Benign tumors.

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Bone Cysts↗

Premalignant tumors and conditions of bone.

Most bone sarcomas arise in apparently normal bone. However, some sarcomas arise in preexisting benign bone tumors or in nonneoplastic conditions. Some of the lesions, such as multiple exostoses and Ollier's disease, have a propensity to develop chondrosarcoma. Rarely does a benign giant cell tumor become malignant without prior irradiation, malignant transformation of other benign tumors, such as osteoblastoma and chondroblastoma, is a medical curiosity. Among nonneoplastic conditions, radiation changes, long-standing chronic osteomyelitis, and Paget's disease have definite premalignant connotations. However, the risk of developing cancer in these conditions is still low.

Adult↗

Hamartoma (mesenchymoma) of the chest wall in infancy.

Chest wall hamartoma, commonly known as mesenchymoma, is very rare in infants and usually present at birth. This lesion is a focal overgrowth of normal skeletal elements, Histologically, it is benign. The radiographic appearance is that of a partially mineralized extrapleural mass involving one or more ribs. Surgical ablation seems to be the proper treatment and is curative. Nine cases of this condition are presented, including long-term follow-up in 4.

Bone Neoplasms↗

Osteosarcoma with small cells simulating Ewing's tumor.

Twenty-four patients who had osseous lesions with histological features of both Ewing's sarcoma and osteosarcoma were studied. Because of their appearance, these lesions have been labeled small-cell osteosarcomas. They appear to represent a definite histological entity and the prognosis may be worse for these lesions than for conventional osteosarcomas. It is most important not to misdiagnose this tumor as Ewing's sarcoma because it appears not to be radiosensitive. Radical surgery and modern adjuvant chemotherapy seem to offer the best chance of cure.

Adolescent↗

Subungual exostoses.

From 1910 through 1975, forty-four patients with subungual exostoses were seen at the Mayo Clinic. Thirty-four of them had the exostosis on the great toe. Forty-three of the patients were treated by local excision and one was treated by amputation of the hallux. Five patients had local recurrence. None of the tumors underwent malignant change. Histologically, the tumors consisted of a proliferating fibrocartilaginous gap that merged into mature trabecular bone at its base. The growth in the cap was so active that is sometimes mimicked sarcoma, but no true anaplasia was seen. The subungual exostoses were uniformly benign, and local excision was the treatment of choice.

Adolescent↗

Keratocysts of the jaw. Clinicopathologic study of 79 patients.

A study of 79 patients with keratocysts of the jaws revealed that 72% of the cysts were in the mandible, predominantly in the ramus. The most common symptom was a painful swelling in the jaw. Enucleation was used in 69.2% of the cases. The recurrence rate was 39%. Total removal of the lining of the keratocyst is essential to prevent recurrence.

Adolescent↗