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Biomedical subjects

D C Funk

Publications and source records attributed to D C Funk.

10 recordsLinked to original sources
PubMed1991

Inheritance of cow durability for linear type traits.

Final score and 14 linear type traits from appraisal by the Holstein Association were analyzed to assess inheritance of cow durability. Change of type scores from first to second parity (second minus first) was cow durability. Score for first parity, change of score from first to second parity, and FCM were simultaneously evaluated with a multiple-trait mixed model for each type trait. First analysis did not allow missing scores of cows for second parity, but subsequent analysis permitted missing data for second parity. When cows were required to have type scores for second parity, heritabilities for change of score were from zero (rear legs and foot angle) to 6% (final score). Genetic correlations of FCM and change of score were from -.35 (rump angle) to .24 (stature). When cows were not required to have type scores from second lactation, heritabilities for change of score were less than 8% for all traits except udder depth (17%). Except for dairy form and fore udder attachment, all genetic correlations of type scores from first lactation and change of score were positive. Seemingly, little new knowledge of linear type traits for ranking of sires was provided by appraisal of cows after first parity.

Aging↗
PubMed1980

Morbidity associated with anomalous origin of the right coronary artery from the left sinus of Valsalva.

Anomalies of the coronary arteries occur infrequently, but can have major clinical consequences. Many reports have described an association between sudden death and origin of the left coronary artery from the right sinus of Valsalva, but origin of the right coronary artery from the left sinus of Valsalva is thought to be benign. Herein, we describe a patient in whom anomalous origin of the right coronary artery from the left sinus of Valsalva was associated with significant cardiovascular morbidity. A 25-year-old man developed complete heart block and myocardial infarction in the distribution of a dominant anomalous right coronary artery free of atherosclerotic lesions. Systolic compression at the origin of the anomalous artery was demonstrated. The left coronary artery was normal. We conclude that anomalous origin of the right coronary artery from the left sinus of Valsalva may be associated with significant cardiovascular morbidity in the absence of atherosclerosis.

Adult↗
PubMed1978

Fracture of a temporary pacemaker electrode catheter.

We have reported an instance of fracture of a temporary bipolar electrode catheter with embolization of the distal fragment to the lung. The patient had no untoward effects for 45 days before death. Autopsy revealed no thrombosis proximal or distal to the catheter fragment. The inability of the catheter to withstand the stress of usage questions the efficacy of its design. Careful inspection of the catheter before its use might have prevented this complication.

Catheterization↗
PubMed1976

Echocardiography in Wolff-Parkinson-White syndrome.

Twenty-six patients with Wolff-Parkinson-White (WPW) syndrome were studied by echocardiography. They were classified into the following WPW types: anterior right ventricular pre-excitation (Type I) - six patients; posterior right ventricular pre-excitation (Type II) - six patients; posterior left ventricular pre-excitation (Type III) - fourteen patients. Twenty-three patients were in WPW at the time of study. Four patients with Type I WPW had abnormal systolic motion of the interventricular septum: three paradoxical and one flat. Patients with Type II and Type III WPW had no septal motion abnormalities related to pre-excitation. Three patients had intermittent WPW, Type III; in all three only minor changes in normal septal motion were apparent on WPW beats. Associated cardiac abnormalities were evident in six patients: two mitral prolapse (one Type II WPS and one Tpe III); one idiopathic hypertrophic subaortic stenosis (Type III); one congestive cardiomyopathy (Type III); one hypertrophic nonobstructive cardiomyopathy (Type I); and one atrial septal defect (Type II). We conclude that abnormal interventricular septal motion may occur with Type I WPW abnormality. Other abnormalities are detectable by echocardiography in a high proportion of WPW patients, but do not appear to be associated with any single Wolff-Parkinson-White type.

Cardiomegaly↗