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Biomedical subjects

D C Kramer

Publications and source records attributed to D C Kramer.

8 recordsLinked to original sources

Dental implants and chemotherapy complications.

The cancer patient receiving chemotherapy often suffers severe oral complications related to the administration of antineoplastic drugs. Cancer patients who also have transmucosal or endosseous dental implants pose special problems for medical oncologists and dentists, both when planning for chemotherapy and when providing supportive care during the course of treatment. The relationship between dental implants and cancer chemotherapy is described and complications experienced by implant patients treated with chemotherapy at The University of Texas M.D. Anderson Cancer Center are reviewed. Recommendations on various aspects of management involving implant evaluation and the removal or retention of dental implants are discussed.

Antineoplastic Agents

You can treat the chemotherapy patient.

Increased numbers of cancer patients are treated with chemotherapy. Patients who receive antineoplastic agents can be at serious risk from dental infections and should be provided appropriate dental care. In many instances, indicated treatment can be accomplished by the patient's private dentist. Certain precautions, however, are necessary when treating dental patients medically compromised by chemotherapy. Dental conditions which may increase morbidity are identified and treatment recommendations are made. Guidelines for dental intervention before, during, and after chemotherapy are discussed with emphasis on the hematologic parameters necessary for safe dental care. The cyclic relationship between chemotherapy and oral complications is also reviewed.

Antineoplastic Agents

Claspless chrome-cobalt transitional removable partial dentures.

Many of the acrylic resin and bent-wire temporary partial dentures in use today produce pathologic changes in the oral mucosa. A method is outlined for the use of chrome-cobalt, instead of acrylic resin, to produce temporary prostheses. The resulting temporary partial dentures are esthetically pleasing and biologically acceptable to the oral tissues.

Chromium Alloys

Cast ejector.

Explore the source record for details and available documents.

Acrylic Resins

Eosinophilic gastroenteritis.

Four patients with eosinophilic gastroenteritis are presented to illustrate the protean manifestations of this disorder. While the cause is unknown, the complications many, and the differential diagnosis often challenging, the treatment is simple and consists of low-dose, alternate-day administration of corticosteroids. Diagnosis depends on gastrointestinal biopsy, which usually can be obtained without surgery.

Biopsy

Seal integrity of hollow-bulb obturators.

Five techniques using various materials were evaluated for their ability to produce a watertight seal between obturator and lid. Leakage was determined by an increase in sample weight above that attributed to sorption and by visualization of water inside the clear acrylic resin samples. A watertight seal was obtained for some samples in each of the test groups. Only the two-flask technique sealed with heat-processed acrylic resin produced a watertight seal in all samples. It was determined that pressure up to 30 psi for 1 hour does not rupture a sealed hollow bulb and immersion under pressure is required to detect leakage of a bulb in a short period of time.

Dental Leakage