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Biomedical subjects

D C Little

Publications and source records attributed to D C Little.

7 recordsLinked to original sources

Life on the farm-children at risk.

BACKGROUND: More than 1 million children live, play, and work on farms, surrounded by animals and machinery. This symbiotic relationship between work and home exposes children to unique risks. METHODS: Children presenting with a farm-related injury (November 1994 to August 2001, 82 months) were included. Trauma registry parameters included injury severity score (ISS); Glascow Coma Scale (GCS); time to presentation; season and day of injury; emergency room, intensive care unit, and total length of stay type; and mechanism of injury; and operations. RESULTS: A total of 1,832 pediatric trauma patients were evaluated. Ninety-four children were identified with farm-related injuries. Mean age was 10.75 years. Mean ISS was 7.38. Three children died. Four children wore protective equipment. Forty-four percent of injuries occurred during summer, 31% during spring, and 55% on weekends. Average time to initial presentation was 39 minutes. A total of 177 minutes elapsed before transfer to regional trauma center. Seventy-two children required admission. LOS was 0 to 28 days, mean, 2.76 days. Twenty-six children (28%) required operations. Injuries included dislocations/fractures (52%), lacerations/avulsions (38%), concussions (31%), contusions (30%), and burns (14%). Mechanism included animals (41%), falls (34%), motor vehicles (28%), all-terrain vehicles (20%), and firearms (4%). CONCLUSIONS: Farm injuries occur most commonly during weekends, summer, and spring months, resulting in significant morbidity. Most injuries required hospitalization. Unless unstable, initial transfer to a regional pediatric trauma center should result in the most cost-effective, prompt, and highest quality of care.

Accidents, Home↗

Long-term analysis of children with esophageal atresia and tracheoesophageal fistula.

BACKGROUND/PURPOSE: For children with esophageal atresia (EA) or tracheoesophageal fistula (TEF), the first years of life can be associated with many problems. Little is known about the long-term function of children who underwent repair as neonates. This study evaluates outcome and late sequelae of children with EA/TEF. METHODS: Medical records of infants with esophageal anomalies (May 1972 through December 1990) were reviewed. Study parameters included demographics, dysphagia, frequent respiratory infections (> 3/yr), gastroesophageal reflux disease (GERD), frequent choking, leak, stricture, and developmental delays (weight, height < 25%, < 5%, respectively). RESULTS: Over 224 months, 69 infants (37 boys, 32 girls) were identified: type A, 10 infants; type B, 1; type C, 53; type D, 4; type E, 1. Mean follow-up was 125 months. During the first 5 years of follow-up, dysphagia (45%), respiratory infections (29%), and GERD (48%) were common as were growth delays. These problems improved as the children matured. CONCLUSIONS: Children with esophageal anomalies face many difficulties during initial repair and frequently encounter problems years later. Support groups can foster child development and alleviate parent isolationism. Despite growth retardation, esophageal motility disorders, and frequent respiratory infections, children with EA/TEF continue to have a favorable long-term outcome.

Esophageal Atresia↗

Culture of the 'aquatic chicken': present concerns and future prospects.

This is not actually a swimming chicken, but rather a fish that fulfils a similar role for subsistence farmers and can also be farmed on a commercial scale. Like the chicken, the tilapiines are meeting protein needs in an affordable way world-wide. However, present farming strategies are struggling to meet ever-rising consumer demand.

Animals↗

Respiratory disease in industry due to B. subtilis enzyme preparations.

Detergent industry workers are known to become sensitized to enzyme preparations added to the products. In a Canadian plant about 25% of 644 employees exposed to airborne commercial B. subtilis enzyme preparations became sensitized. Skin tests with a number of antigens, including purified enzyme preparations, illustrated differences from person to person in the components to which there was sensitization. The presence of respiratory symptoms related to the industrial exposure was reported much more commonly among sensitized workers. Among employees obliged to miss work, FEV(1) values after 24 months were considerably higher than those obtained during the time of initial difficulties. Blood eosinophilia was observed in sensitized workers. Serum IgG antibodies to the enzyme preparations were demonstrable in most sensitized individuals but did not provide a reliable index of sensitization or of the symptomatic state.

Absenteeism↗