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Biomedical subjects

D C Murphy

Publications and source records attributed to D C Murphy.

26 records · Page 2Linked to original sources
PubMed1980

Antimuscarinic agents: furan analogs of benzilate esters.

The methiodide and ethiodide salts of 5-(dimethylaminomethyl)- and 5-(diethylaminomethyl)-alpha, alpha-diphenylfurfuryl alcohol were prepared, These compounds may be considered as furan analogs of dialkylaminoethyl benzilate alkiodides. The pA2 values of these compounds as antagonists of acetylcholine were determined on rat jejunum preparation. All four compounds were significantly less potent than the analogous ester antimuscarinic lachesine. The furan ring cannot be substituted for the ester moiety of typical antimuscarinics. Possible modes of binding by antagonists to the receptor proposed previously are considered that might account for this less-than-expected antimuscarinic activity.

Animals↗
PubMed1966

Industrial hygiene.

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Environmental Health↗
PubMedDate not supplied

Ergonomics and dentistry.

Since 1992 the Occupational Safety and Health Administration (OSHA) has been preparing Federal legislation concerned with ergonomic hazards in at-risk workplaces. Although multifactorial in nature, there is sufficient evidence in the scientific literature to document an association between the practice of dentistry and a variety of musculoskeletal disorders. There are preventive strategies already known and available to us. Should dentistry be considered an at-risk profession and be required to comply with the forthcoming standard, or is self-monitoring sufficient?

Bone Diseases↗