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D Cardozo

Publications and source records attributed to D Cardozo.

5 recordsLinked to original sources

[Epidemiologic studies of cerebellopontine angle tumors surgically treated in Maracaibo, Venezuela, in 1985-1999].

OBJECTIVE: To analyze the epidemiological, clinical and neuropathological data of cases of cerebellopontine angle (CPA) tumors. MATERIAL AND METHODS: The clinical records, neuroimaging and neuropathological studies of 50 patients with diagnosis of CPA tumor operated in different hospitals of Maracaibo, Venezuela, during the lapse January 1st, 1985-December 31, 1999 were reviewed. The variables age, gender, side of the lesion and neuropathological diagnosis were analyzed. RESULTS: A 2:1 female to male ratio was observed. Median age was 48 +/- 12.7 years. Acoustic neuromas (AN) represented 48% of the cases, whereas nonacoustic neuroma tumors (NANT) made up for the rest (52%). Meningiomas were the second more commonly diagnosed lesions, they constituted 32% of the cases. Meningiomas and AN were more frequent in women, their ratios being 7:1 and 1.6:1, respectively. In 60% of the cases the signs and symptoms became eloquent in patients of the fourth and fifth decades of life. CONCLUSIONS: The difference between our results and the ones previously reported in the medical literature are due in part to the predominance of female patients in our series. Endocrinologic, genetic and biochemical factors could also be responsible; nevertheless, this does not constitute the objective of the present study.

Adult↗

Extraventricular cerebral anaplastic ependymomas.

BACKGROUND: Anaplastic ependymomas are considered to be uncommon cerebral tumors by most authors. We have had the opportunity to study 34 cases of such lesions in 13 years. METHODS: 34 cases of anaplastic ependymoma operated in different hospitals of Maracaibo, Venezuela, during the period of 1983-1995 were analyzed. Cases of ependymoblastoma were excluded. RESULTS: Adult patients made up most of the present series. All patients harbored supratentorial growths in locations distant from the ventricular system. The microscopic pattern was of limited value to establish prognosis, for there was no constant correlation between the histologic features and tumor relapse; only in sporadic cases in which high cell density and conspicuous mitotic activity were maximally expressed, did tumor relapse occur shortly after removal of the lesion. CONCLUSION: This type of paradoxical behavior being the rule makes all attempts at predicting prognosis in these entities a disappointing task.

Adolescent↗

[Causes of dementia in Maracaibo, Venezuela: a re-evaluation].

INTRODUCTION AND OBJECTIVES: In a previous report we analyzed the causes of dementia in an autopsy population from four hospitals of Maracaibo, Venezuela. Our results showed that vascular dementia (VD) accounted for 86.7% of all clinically diagnosed demented patients, whereas no cases of Alzheimer's disease (AD) were neuropathologically demonstrated. Six years later, we undertook a similar study, in order to re-evaluate the frequency of the different causes of dementia in our country. MATERIAL AND METHODS: We studied 611 adult brains obtained from autopsies performed during the period 1992-1998; 39 of these came from clinically demented patients. RESULTS: Vascular dementia was disclosed in 33 cases (84.6%), five cases (12.82%) showed evidence of specific causes for dementia other than VD or AD, and in one of the cases (2.56%) the neuropathological changes were specific for AD. CONCLUSIONS: Our current results confirm the conclusions of our previous study and contrast with the vast majority of reports in the medical literature regarding the frequency of the different causes of dementia, except for studies from China, Japan and Russia that yielded similar findings as ours. At present, further investigations are being undertaken in order to come up with possible explanations for these differences.

Adult↗

Solitary fibrous tumor of the meninges.

Intracranial fibrous tumors are unusual growths that occur almost exclusively in young individuals. Most of these lesions are intra-axial, however, on extremely rare occasions they arise from the leptomeninges and compress the adjacent brain. The authors report the case of a benign solitary fibrous tumor of the meninges in a 14-year-old girl who presented with a 5-month history of generalized headaches. NMR imaging displayed a left parietal mass, which mimicked a meningioma.

Adolescent↗