PubMed HealthSearch

Biomedical subjects

D Cardus

Publications and source records attributed to D Cardus.

8 recordsLinked to original sources

Judgments of the potential benefits of rehabilitation research.

A critical step in a project to develop a benefit-cost approach to evaluating proposed rehabilitation research has been to specify the potential benefits of such research in a reasonably systematic and comprehensive manner. The purposes of this study were: (1) to assess the contemporary relevance of 46 benefit factors yielded by a 1973 survey: (2) to acquire judgmental data to reduce these factors to fewer and more generic 2nd-order factors: (3) to compare 7 different rehabilitation role groups in terms of how the potential benefits of rehabilitation research are valued. "Hierarchical clustering" analyses of similarity judgments by 96 participants yielded 18 2nd-order benefit factors. A number of reliable differences were identified among the role groups regarding the value placed upon specific potential benefits of rehabilitation research.

Cost-Benefit Analysis

Electronic processing of cardiac rehabilitation data.

With the incidence of ischaemic heart disease at epidemic levels and rising, techniques for detecting, predicting, and rehabilitating the condition of cardiac dysfunction are constantly under development. One technique, that of exercise stress testing, has been used in recent decades in the prediction, detection, and rehabilitation of cardiopulmonary disease. However, ergometric studies in this regard have been hampered by the tedium of physiologic data collection and analysis. With the advent of automated digital and analogue computation procedures and equipment, such data can be both operated on real-time for immediate display or stored for post-exercise and patient-history studies. Such automated data manipulation provides an systematic and comprehensive testing of each patient and permits a much greater case-load. In addition, special computer programs can compile and index specific parameters from a large sample size to facilitate statistical surveys of selected patient populations. The results of such statistical analyses can, if desired, be automatically printed out in a graphical form.

Computers

Metabolic effects of sodium restriction and thiazides in tetraplegic patients.

The metabolic effects of sodium restriction, alone or with thiazide, were studied in 12 healthy subjects, in 24 tetraplegics during the intial 8 months of paralysis (early) and in 16 others during the subsequent period (late). The diuresis caused by both treatments led to more haemoconcentration in early than in late patients. In contrast with the healthy subjects on low sodium, the tetraplegics had a delayed urinary sodium retention and no fall in calciuria. During thiazide, urinary sodium depletion occurred early and the urine calcium fell after 3 days in all tetraplegics. During both treatments, aldosterone and renin increased more in early patients than in the other groups. The clinical implications of inducing dehydration and a sustained stimulation of the renin-angiotensin-aldosterone axis in recently injured tetraplegics with severe orthostatic hypotension are discussed.

Adolescent

Cardiac evaluation of a physical rehabilitation program for patients with ischemic heart disease.

A reconditioning exercise program that was applied to group of 12 coronary patients resulted in an increase of their tolerance to physical work and of their maximal working capacity. In some instances the improvement in physical condition was accompanied by changes in indicators of cardiac function which suggest that an improvement in myocardial performance also occurred. Although some evidence of this has been presented, more studies are needed for substantiation. It is believed, on the other hand, that to explain the improvement of the patient, it is not necessary to invoke an improvement of myocardial performance. An improvement of patient's tolerance to physical work may also be explained by extracardiac mechanisms that produce changes in arterial peripheral resistance, regional blood flow distribution, overall mechanical efficiency, muscle capillarization, fiber size and mitochondrial enzymatic activity, patterns of sweating, adaptation between pulmonary ventilation and circulation, work of breathing efficiency, autonomic nervous system balance and in the adaptive responses of the neuroendocrine system which mediate between psychic and physiological behavior. All of these changes have been observed in healthy individuals submitted to physical training. It is plausible to assume that they may also occur in the patient with ischemic heart disease. What is to be shown is which one or which ones of these mechanisms prevail in a given individual.

Adult