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D Castro

Publications and source records attributed to D Castro.

84 records · Page 5Linked to original sources

[Endoscopic polypectomy of the upper digestive tract].

From 1985 to 1987 we performed 82 endoscopic polipectomies in 80 patients. In this paper we refer the technics, epidemiological data and macro and microscopical findings of the resected specimens. Two patients with gastric cancer were treated in this way, these patients had formal surgical contraindication. In two patients in whom the endoscopic biopsies could not render a definitive diagnosis (cancer or atypical epithelium), the study of the resected tumor permitted the diagnosis of atypical epithelium, so two gastrectomies were avoided. Among our resected lesions we found 55 of inflammatory type, 6 adenomas and 7 atypical epithelium. We consider that this is a useful method for the diagnosis and treatment of some elevated lesions. Although this is not the treatment of choice for the elevated early cancer, it could be used to treat cancerous tumors in patients with high surgical risk.

Adult↗

[Asymptomatic stomach ulcer].

The purpose of this paper is to evaluate the frequency and some of the clinical and epidemiological characteristics of asymptomatic gastric ulcer, found in persons who attend the Center for Control of Gastrointestinal Cancer of San Cristóbal, Venezuela, as part of a gastric cancer mass screening program. 350 patients with active peptic ulcer were found, 176 duodenal and 174 gastric, diagnosed by means of endoscopy. Of the patients with gastric ulcers, 67 (38.5%) had no symptoms. This group of asymptomatic patients were analyzed regarding age, sex, place of residence, type of work and also the location of the ulcer and the histology. We conclude that this entity is frequent in our region that it is associated with agricultural workers and house wives. It is necessary to continue a prospective periodical evaluation of these patients in order to understand the natural history of the entity.

Adult↗

[Macroscopic and histopathological aspects of atypical gastric epithelium].

Atypical Epithelium is a localized lesion, which has histological and macroscopic findings similar to gastric cancer. In this paper we evaluated 44 cases of atypical epithelium studied and treated in our institute. We found 3 cases of atypical epithelium associated with early gastric cancer. That is 2.66% of the total of all cases. We established the relationship of these lesions and following variables: age, size, localization, macroscopic shape and intestinal metaplasia. We found atypical epithelium in patients older than 50 years old, most of then smaller than 2 cm., localized in antrum and body gastric, and macroscopically were slight elevated lesions. Histologically all of them had intestinal metaplasia.

Adenocarcinoma↗

[Gastric leiomyoblastoma. Histomorphologic and immunologic analysis of 3 cases].

We present three cases of Leiomioblastomas of stomach, diagnosed at the unit of Pathology of the Gastrointestinal Cancer Center "Dr Luis E. Anderson" -San Cristóbal-Táchira State Venezuela. The lesions are analyzed from the clinical, morphological and immunohistological points of view, utilizing Queratine and Vimentin techniques. This neoplasm is not frequent but it is interesting because its biologic behavior not always correspond to its histology-pattern.

Humans↗

[Endoscopic sphincterotomy experience at the Cancer Control Center].

Endoscopy Sphincterotomy is an important therapeutic procedure in the treatment of some biliary and pancreatic disorders. In this paper, we report our experience over this subject. In our patients the main indication to perform this procedure was common bile duct stones; they were 83% of the total cases. In those cases, 67% were residual stones after cholecystectomy by laparotomy and laparoscopy. We performed sphincterotomy in 33% of patients with gallbladders in situ. In five patients (7.57%), we made the diagnosis of Oddi's sphincter dysfunction taken in account clinical, biochemical an radiological findings. No manometric measurements were done. We found some unusual cases, such as: choledococele and Sump syndrome. In five patients we had complications, 3 of them bled and the other two developed edematous pancreatitis. All these complications were solved with medical treatment.

Adult↗

[The use of urea carbon 14 in breath tests as diagnostic method for Helicobacter pylori infections].

The Helicobacter Pylori has been indicated as a pathologic agent in the pathogenesis of antral gastritis, gastric and duodenal ulcers and probably in gastric cancer. Due to the high incidence of this infection in our place, we decided to look for a diagnostic method quick to perform, sensitive, reliable and no invasive. The breath test of 14C urea, based in the production of urea by the H. Pylori, represents this alternative. We have found, using does of 1 microCi, a high correlation with the diagnosis of H. Pylori by biopsies. We determined as negative less than 100 DPM, doubtful between 100 and 200 DPM and positive more than 200 DPM. The high pick of the curve keeps tight relation with the degree of infection. We checked this when we suppressed the H. Pylori with bismuth subsalicylate. The breath 14C Urea test showed high sensitivity (100%) and specificity (85.71%). We conclude that this breath test is an alternative way of diagnosing and follow up for H. Pylori infections. It is highly sensitive, reproducible and no invasive.

Adult↗

[Macroscopic aspect and depth in early gastric cancer].

Depth of invasion in Early Gastric Cancer (E.G.C.) is very important to be evaluated. We reviewed 78 cases of E.G.C., in patients of our program that were operated on. We established the relationship among three macroscopic variables (localization, size and macroscopic shape) and depth of invasion. We realized that the lesions located in the fundus, though diagnosed less frequently, has more tendency to invade the submucosa (50%), in relation to other localizations. We did not find a significant statistic relation chi 2 = 3.76 P: .58 df:5 between size and invasion. The macroscopic types IIa + IIc and the E.G.C. type III have tendency to further invasion (58.8 and 66.67%). The polypoid lesions Type I and IIa are mostly intramucosal, so they could be treated endoscopically in high risk and old patients.

Gastric Mucosa↗

[Use of role-playing in child psychotherapy and psycho-pedagogy].

Spontaneous role-playing in children stands as a contribution in generating and in improving social behaviors. Spontaneous role-playing is a part of the child's maturing process. Its characteristics: it does not follow any logical pattern; it is frequently repeated; its emotional involvement is important, without ambivalence. Educational role-playing attempts to help the child in coping with a peculiar interpersonal situation. Therapeutical role-playing may be used in helping children suffering from a definite impairment of social skills--or from any psychological or medical problem. We report an example of the use of therapeutical role-playing in a group of diabetic children suffering from disorders in interpersonal relationships arisen at the time of the onset of their physical illness.

Adolescent↗

[Inflammatory response associated with Helicobacter pylori infection in gastric mucosa with intestinal metaplasia in a population in high risk for gastric cancer].

Intestinal Metaplasia (IM) and Helicobacter Pylori (HP) infection had been related to gastric carcinogenesis. With the intention to know the relationship among HP infection, IM and inflammatory response of the mucosa in an area of high prevalence of gastric cancer, we studied 800 persons that attended the Gastric Cancer Mass Survey, ongoing in the State Tachira, Venezuela, since 1981. Out of these subjects, 259 had histology diagnosis of IM (32.4%) 52.1% were IM type Y, 19.3% type II and 22.8% type III (sulfomucin secretory). Histology demonstrated with Giemsa stain HP in 94.6% of the cases. Association between HP and inflammation response in gastric mucosa with IM, was statistically significant (p = 0.001). The are heavier bacteria overload in IM type I than in type III although it is not statistically significant. We ponder if gastric mucosa inflammation due to HP, conditions development of IM as a hostile way of the gastric environment to restrain bacterial growth. This phenomenon ally with other oncogeneous factors could induce to premalignant lesions and eventually gastric cancer.

Adult↗

[Early gastric cancer in the remnant stomach. Case report].

Patients with partial gastrectomy are a High risk group to develop gastric cancer. Risk is higher in remnant estomach after partial gastrectomy by malignancy than benign disease. We present a case of a male patient, 64 years old, who was admitted in our Hospital with Hypovolaemia. We found during Endoscopic examination early gastric Cancer IIc + III type in the site of anastomosis. Partial gastrectomy was performed in this patient by Duodenal ulcer 11 years ago.

Adenocarcinoma↗