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Biomedical subjects

D Cepowicz

Publications and source records attributed to D Cepowicz.

5 recordsLinked to original sources
PubMed2004

Assessment expression of the adhesion molecules, CD134 and CD137, in patients with colorectal cancer by flow cytometry.

The aim of the study was to assess the expression of adhesion molecules, CD134 and CD137, in the peripheral blood in correlation with clinical advancement, the histological grade, the size and type of tumour growth, tissue infiltration, and lymph node and metastases to lymph nodes and liver. The study involved 28 patients with primary colorectal cancer. The expression of both molecules was investigated on the day of the surgery, before the procedure and ten days after the operation by means of flow cytometry. The expression of CD134 was markedly higher, compared to CD137, both on the day of the surgery and ten days after the operation. A significant increase was observed in CD134 expression ten days after the surgery. CD137 expression increased with the higher stage of clinical advancement, but decreased with the enhancement of colon wall infiltration. CD134 showed a similar expression for all the stages of tumour clinical advancement.

Antigens, CD↗
PubMed2004

Molecule CD44 variant 10 expression in lymphocytes infiltrating tumour tissues and epithelial cells in patients with colorectal cancer.

The aim of this study was to evaluate the expression of CD44v10 in colorectal tumour cells and in lymphocytes infiltrating the tumour (CD45+). Samples of tumour tissue (TT), as well as of healthy tissue (HT) and of tumour adjacent tissue (TAT), were obtained from 20 patients. An evaluation of CD44v10 expression was performed in a flow cytometer. The mean value of the percentage of CD45+ with co-expression of CD44v10 was significantly higher in the lower stage of the tumour (pT). The mean value of the percentage of epithelial cells with CD44v10 co-expression was significantly higher in pN2 than in pN1 stage. Only in TAT the mean value of the percentage of epithelial cells and CD45+ with tCD44v10 co-expression was significantly lower in the higher degree of histological malignancy. It is supposed that CD44v10 takes part in local cancer progression.

Colorectal Neoplasms↗
PubMed1997

[Laparoscopic cholecystectomy conversion--causes and surgical procedures].

From September 1993 tol May 1997 360 laparoscopic cholecystectomies have been performed in patients aged 17-74: 318 women (88.3%) and 42 men (11.7%). 19 of them (5.3%) required a conversion to open surgery. In 13 cases (13.6%) conversion was caused by technical difficulties. In the other 6 (1.7%) was caused by intraoperative complications. While converted 15 simple cholecystectomies were performed, 2 with T-tube drainage of bile ducts, 1 with anastomosis choledochoduodenalis and 1 with partial stomach resection (Rydygier method). In all cases adhesions were divided. None of the patients died. Authors believe that LCh can be performed safely on most of the patients with chronic and acute cholecystitis.

Adolescent↗
PubMed1996

Surgical treatment of prolapse of the rectum--evaluation of distant results.

In the years 1972-1995 41 patients suffering from prolapse of the rectum were operated according to the Moore method. The method is based on the observations which suggest that the cause of prolapse is intestinal intussusception which can be prevented by translocating the anus under the pubic joint. The observation time is from 1 to 23 years. Two patients were reoperated; one-as a result of a recurrence of rectal prolapse and one due to a post-operative adhesive ileus. One patient died as result of peritonitis following an overlooked microperforation in the rectal wall. In the case of the remaining patients, the treatment was fully successful. Regular defecation cycle as well as incontination of stool and flatus returned and the anal sphincters almost fully regained their tension in comparison to the pre-operative state. Early and distant results of surgery of prolapse of the rectum are satisfactory.

Adult↗