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Biomedical subjects

D Cloarec

Publications and source records attributed to D Cloarec.

40 records · Page 3Linked to original sources
PubMed1986

[Hormone immunocytochemical studies of 46 endocrine tumors of the pancreas in 24 patients].

The aim of this retrospective study was to correlate the results of hormonal immunocytochemistry of 46 endocrine tumors to the corresponding clinical syndromes in 24 patients. They were divided as following: 14 cases of insulinoma, 3 cases of Zollinger-Ellison syndrome, 1 case of glucagonoma, 1 case of carcinoid syndrome and 5 cases without any obvious endocrine manifestations. Each tumor was tested with anti-insulin, anti-glucagon, anti-pancreatic polypeptide, anti-vasoactive intestinal peptide, anti-gastrin immune sera according to the peroxidase-antiperoxidase method. The presence of insulin was proved in 13 of 14 cases of insulinomas and the presence of gastrin in 2 of 3 cases of Zollinger-Ellison syndrome. Among the 5 asymptomatic cases, a somatostatinoma and a vipoma were individualized. More than 50 p. 100 of the tumors showed plurihormonal secretion with one predominantly secreted hormone responsible for the clinical syndrome. This study demonstrated the diversity of the hormonal secretion by some tumors and their metastasis in the same patient. Malignant insulinomas correspond either to poorly secreting tumors or to plurihormonal tumors secreting gastrin and glucagon as well.

Adenoma, Islet Cell↗
PubMed1986

[Ogilvie's syndrome: results of endoscopic exsufflation in a series of 29 cases].

The aim of this study was to assess the value of endoscopic decompression of the colon in a series of 29 patients affected with Ogilvie's syndrome. During the first period (1980-1982), 14 patients were treated by colonoscopic decompression alone. During the second period (1982-1985), 15 endoscopic decompressions were systematically completed by intubation of the colon. The tube was removed after 2 to 13 days. Whatever the procedure, endoscopic decompression was successfully achieved in all cases. The death rate (8/29) and number of cecostomies (2/29) were similar in the two groups of patients. Only one death was directly related to Ogilvie's syndrome itself, whereas 7 patients died from other severe underlying diseases. However, colonic dilatation recurred in 6 patients in the first group and in one patient in the second group (p less than 0.05). No complications due to the endoscopic procedures occurred in this series. It may be concluded that endoscopic treatment of Ogilvie's syndrome is a safe and effective procedure. Our results also suggest that colonoscopic intubation should be used prophylactically in order to avoid recurrences, frequently observed after simple endoscopic decompression.

Acute Disease↗
PubMedDate not supplied

[The role of the argon laser in the treatment of condylomata acuminata of the anal margin and canal].

Condyloma acuminata of the anal margin or anal canal raise therapeutic problems as soon as they become important. In this study, we report the results obtained by 24 patients after Argon-ion laser therapy. This laser, the beam of which is mainly absorbed by haemoglobin allowed us to cure 91,7 percent of our patients. This results was obtained in one (14 patients) or two sessions (10 patients) with at least 3 months as follow-up. Furthermore we can notice the excellent quality of cicatrization and the complete lack of incidents during or after the treatment. So argon laser could be a new kind of treatment used preferentially in extensive genital warts.

Adolescent↗