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Biomedical subjects

D Coomans

Publications and source records attributed to D Coomans.

50 records · Page 3Linked to original sources
PubMed1983

[The French experience with moxalactam in pneumology].

Twenty-nine patients, aged 19 to 87, were treated for an infection of the lower respiratory tract (pneumonia, bronchopneumonia, bronchitis, pulmonary abscess, pleuritis) due to a pathogen with in vitro sensitivity to the antibiotic (pneumococcus, hemophilus, anaerobic organisms . . .). Patients were given Moxalactam as the only antibacterial treatment. In most instances, excellent results (24 successes, i.e. 84% of cases) were recorded with two daily intramuscular injections of 1 g each. Biologic tolerance was satisfactory. Possible clinical side-effects are rashes and local pain during the injection. We conclude that Moxalactam is very effective in severe lower respiratory tract infections, with a daily dosage of 30 mg/kg.

Adolescent↗
PubMed1983

[Current clinical aspects of tuberculous infection].

Case records of 37 patients with tuberculosis were analysed, out of 4 000 patients admitted to our department of internal medicine over a period of four years. The most common localisations are still pulmonary, but these are often atypical. Lymph node involvement is found in immigrants. More exceptional localisations (liver . . .) are reported. Tuberculosis has not yet become obsolete.

Female↗
PubMed1983

Comparative study of topological and linear free energy-related parameters for the prediction of GC retention indices.

The different molecular connectivity indices were considered as to their capacity for describing GC retention indices of a data set consisting of molecules of different chemical families. 1 kappa describes best the chromatographic behavior on nonpolar stationary phases, whereas 3 kappa p in combination with an electronic parameter (sigma) yields the best results when using the polar stationary phases.

Chemical Phenomena↗
PubMed1982

[Inappropriate secretion of antidiuretic hormone (ISADH) after head injury (author's transl)].

Two new observations of ISADH following head injury are described. A review of the medical literature is presented. Reports of ISADH after head injury are rare in comparison to the frequent occurrence of hydroelectrolytic disorders in the same situation. Attention is drawn to misleading clinical pictures, suggestive of neurosurgical conditions. Intracranial hematoma is frequently associated with ISADH and should be looked for in patients who fail to respond to therapy.

Aged↗
PubMed1977

Application of linear discriminant analysis to the differentiation of pure milk from different species and mixtures.

Discriminant analysis is used to identify different milk samples on the basis of the gas chromatographic data for fatty acids in 20 samples each of milk fat from cows, sheep, and goats. The method can differentiate mixtures and pure milks with a high degree of correct classifications. A good discrimination can also be obtained by using a reduced set of variables. The method is useful for the interpretation of gas chromatographic data and should allow a higher proportion of correct classifications than is possible by visual inspection of the chromatograms.

Animals↗
PubMedDate not supplied

Localization of lead and fluoride in cultured tooth germs by laser microprobe mass analysis.

Trace elements can influence dental health, possibly by altering tooth resistance during preeruptive development. Therefore, it was investigated whether lead and fluoride would be incorporated into the calcifying matrices or the cellular parts of tooth germs in vitro. Using laser microprobe mass analysis, the localization of lead and fluoride was studied in the different layers or tooth germs that had been cultured in a medium to which PbCl2 of NaF had been added in different concentrations. Both elements could only be detected in the dentine layer. Hence, the enamel organ in the secretory stage of tooth development excludes lead and fluoride from the enamel, even when enamel formation by the ameloblasts is visibly disturbed. Furthermore, there seemed to be a process of saturation in the accumulation of lead and fluoride in the dentine.

Animals↗
PubMedDate not supplied

Seasonal variation of stable intrathyroidal iodine in nontoxic goiter disclosed by x-ray fluorescence.

The intrathyroidal stable iodine (ITI) determined in 776 patients chosen at random. Ninety % of these patients presented with nontoxic goiter. Curve-filtering analysis techniques showed a seasonal variation in ITI: an acrophase was found in April/May, a nadir in September/October. The possible relationship of this seasonal variation with the intake of iodine or alimentary antithyroid substances are discussed, as well as possible relationship with variation in chronic TSH stimulation related to ambient temperature.

Fluorescence↗
PubMedDate not supplied

[Diffuse hemangioma of the liver. An unsuccessful cobalt therapy (author's transl)].

With reference to the observation of a diffuse hemangioma of the liver in an adult patient, the authors note the various means of diagnosing the disease and list existing therapeutic possibilities. In the typical case, a laparoscopy points out the tumour but is not sufficiently precise to detect a possible extension. The angiography shows pathognomonic images. Isotopic methods are not specific. Treatment is poorly codified and may take the form of a ligature of the artery, embolization or irradiation. The latter, the most widespread type of treatment may cause more or less severe complications.

Cobalt Radioisotopes↗
PubMedDate not supplied

[Still's disease in the adult (author's transl)].

Four new cases of adult Still's disease have been observed in the past three years. Clinical and biological features are high fever, polyarthralgia, macular rash on forearm, pericarditis, splenomegaly, lymphadenopathy, alopecia, anemia, hyper-leucocytosis, raised ESR. Transient neurological findings may also be observed with abnormal reflexes, cranial nerve paralysis. High dose steroids treatment can be used in case of systemic involvement. The long term prognosis is usually good with treatment. In conclusion, the diagnosis of Still's disease is essentially clinical and should not be mistaken for septicemia.

Adolescent↗