Topical aldose reductase inhibitor.
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Administration, Topical↗
Biomedical subjects
D Coster
Publications and source records attributed to D Coster.
Pterygium--an ophthalmic enigma.
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Cell Division↗
Paraquat causes chronic ocular surface toxicity.
We describe a case of topical exposure to a commercial solution of paraquat. Chronic, severe ocular surface destruction resulted, probably due to absorption of the herbicide into the surface tissues, facilitated by a surfactant present in the preparation, and to intracellular redox cycling of the paraquat cation. Ocular paraquat toxicity is described and explained in the context of the toxicity of systemic absorption.
Absorption↗
Metastatic right atrial tumor in colon cancer with superior vena cava syndrome and tricuspid obstruction.
Metastatic colon carcinoma of the heart is a rare diagnosis, and an uncommon finding at autopsy. This report describes a patient with a huge intracavitary colonic metastasis of the right atrium causing both a superior vena cava syndrome and an obstruction of the tricuspid valve. To our knowledge, no similar case has been previously reported.
Adenocarcinoma↗
Patterns of superficial keratopathy.
Corneal surface abnormalities are commonly encountered in ophthalmology and are manifestations of a wide range of underlying disease processes. The diversity of both clinical presentation and morphological appearance requires a systematic approach to the identification and management of these superficial corneal changes. Accurate diagnosis of superficial keratopathy requires skillful observation to seek the most characteristic clinical sign, a deductive thought process based on a knowledge of disease patterns, and occasionally the use of laboratory procedures to confirm the working diagnosis. We have classified changes of the corneal surface into five categories based on the clinical pattern (punctate, dendritic, plaque, vortex, and linear). We show how pattern recognition, with the aid of clinical presentation, history, and appropriate investigations, can lead to accurate diagnosis and initiation of proper management.
Adenovirus Infections, Human↗
Adenine arabinoside in the management of herpetic keratitis.
Ara-A is an effective antiviral agent in the treatment of herpetic ulceration. Its use leads to a quick and high cure rate, and clinical resistance is low. It can successfully be used in cases showing complications after treatment with other antiviral agents.
Clinical Trials as Topic↗