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D D Banker

Publications and source records attributed to D D Banker.

At least 19 recordsLinked to original sources
PubMed1992

Study of bacterial pathogens causing diarrhoeal disease in Bombay with special reference to their antibiotic sensitivity pattern.

Diarrhoeal disease is an important cause of morbidity and mortality in developing countries, especially among children. In a study of 720 faecal samples from acute diarrhoeal patients various bacterial pathogens were isolated. An account is given of their antibiotic sensitivity pattern. Many of the E. coli, Salmonella and Shigella strains were found to be multidrug resistant. This resistance was transferable and plasmid mediated. A few of the E. coli strains isolated from healthy controls also showed multidrug resistance.

Adult↗
PubMed1991

Prevalence of hepatitis B surface antigen & its subtypes in high risk group subjects & voluntary blood donors in Bombay.

HBsAg positive subjects belonging to high risk groups and voluntary blood donors were analysed for prevalence of HBsAg among various groups of subjects for ascertaining the carrier status among the voluntary blood donors, HBsAg subtype distribution, and association of HBsAg with blood groups and caste or religion. The prevalence of HBsAg varied from 2.02 per cent in voluntary blood donors to 58.38 per cent in patients of acute viral hepatitis. 70.5 per cent subjects had subtype 'ay' while 23.9 per cent of the subjects had subtype 'ad'. We also found compound 'ady' subtype in 5.6 per cent of our subjects. HBsAg/adr, a subtype not usually prevalent in India, was found in 30 of the 90 'ad' sera. Co-occurrence of HBsAg and anti-HBs was noted in 9 subjects. Homotypic anti-HBs was found to occur together mainly in voluntary blood donors, while heterotypic anti-HBs was found to occur together mainly multi-transfused patients. There was no significant correlation between HBsAg and blood group antigens and a relatively higher incidence of HBsAg among the Jain community was observed.

Blood Donors↗
PubMed1991

Rapid cultivation of Mycobacterium tuberculosis in Veeraraghavan's liquid medium.

2015 clinical samples were screened for M. tuberculosis culture in Veeraraghavan's liquid medium V (T). The liquid medium is a synthetic medium rich in amino acids, vitamins, sugars and mineral salts. Initially 111 consecutive samples of sputum and various body fluids were cultured in both LJ medium and liquid synthetic medium for comparison. As liquid medium gave satisfactory and quicker results the subsequent 1904 samples were cultured only on liquid medium to determine its usefulness in routine work. A total of 215 of the 243 ZN smear positive samples successfully grew within 48 hours in the liquid culture medium. Drug sensitivity was performed on the positive cultures at 10, 20, 40 and 80 micrograms/ml concentrations in the liquid medium with RNA. The sensitivity results were obtained within next 48 hours. The sensitivity tests on the cultures under study revealed highest sensitivity to Rifampicin and lowest to Isoniazid. Identification and pigment production of the mycobacterial culture was also done successfully in Veeraraghavan's liquid medium. The liquid medium is cost-effective and is recommended for routine use.

Bacteriological Techniques↗
PubMed1990

Apolipoproteins.

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Apolipoproteins↗
PubMed1990

Hepatitis B and delta viruses in fulminant hepatitis.

From June 1985 to 1989, we studied 39 cases with fulminant viral hepatitis. These included 32 cases due to hepatitis B, of whom 27 died. Twenty of the 32 cases were positive for delta antibody, and all of them died. Four cases who died were negative for IgM anti-HAV, HBsAg and IgM anti-HBc and were classified as NANB. Thus, a total of 31 patients died. Hepatitis B and delta virus infection were the major risk factors for fulminant hepatitis and eventual death.

Adult↗
PubMed1983

Antimicrobial resistance and incompatibility groups of R plasmids in Salmonella typhimurium isolated from human sources in Bombay from 1978 to 1980.

Salmonella typhimurium isolated in Bombay from fecal samples of 145 patients suffering from gastroenteritis (group 1) and from the cerebrospinal fluid, feces, or blood of 42 patients with systemic salmonellosis (group 2) were examined for the antimicrobial resistance and incompatibility groups of their R plasmids. Multiple drug resistance was encountered in 88.9% of the isolates from group 1 and in all the isolates from group 2. The resistance found was mainly against ampicillin, chloramphenicol, kanamycin, streptomycin, sulfonamides, and tetracycline. In addition to these resistances, a number of isolates were also resistant to sulfamethoxazole-trimethoprim and gentamicin. The overall isolation frequency of strains resistant to these last drugs was significantly higher in group 2. The drug resistance in 95.3% of the isolates from group 1 and in all the isolates from group 2 was plasmid mediated. Incompatibility grouping of the R plasmids and phage typing of the isolates indicated that a clone of S. typhimurium with phage type pattern 66/122/untypable carrying Tra- IncF1me, Tra- Inc1, and Tra- Inc2 plasmids was most prevalent in Bombay from 1978 to 1980, and examples of this clone, especially those resistant to sulfamethoxazole-trimethoprim and gentamicin, were most often responsible for severe septicemic infection. A majority of the remaining S. typhimurium isolates were untypable and harbored plasmids of groups IncC, IncF1me, IncFII, IncH1, IncH2, IncI1 and IncI2; these isolates were rarely associated with systemic infection.

Drug Resistance, Microbial↗