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Biomedical subjects

D D Dedo

Publications and source records attributed to D D Dedo.

18 recordsLinked to original sources

Computerized slide show for the 1990s lecturer.

One of the most difficult and time-consuming tasks of writing and presenting papers is the review and coordination of patient photographic records. For years, not only has the 35-mm slide been the means of photographic storage for patient records, but also the standard for illustrating lectures and presentations. This current method is cumbersome and time consuming. We have used existing software of the Cameo II and imaging system to prepare, create, and present illustrations for lectures. Patient images are digitalized from any source (eg, photographs, slides, video tape) and electronically stored in the computer along with the computer-generated illustrations. When a lecture is prepared, the images are arranged sequentially in an electronic carousel. This computerized program is recorded on video tape and simply played through the video projector during the presentation to display the images. This system is more efficient since any stored image can be displayed instantaneously in any order without the handling of 35-mm slides. The only limitation of this system is the user's imagination. As the current trend in computer technology continues with high-resolution TV and video systems, the 35-mm slide presentation will become obsolete.

Education, Medical↗

Liposuction of the head and neck.

It has been 4 years since liposuction was introduced as a surgical technique to sculpture and remove the subcutaneous layer of fat in the head and neck. Otolaryngologists and facial plastic surgeons have been reluctant to incorporate this procedure into their surgical armamentarium, fearing that liposuction would be a passing fad and not live up to original expectations. Basic animal research and clinical studies now show that liposuction is a safe, fast, and effective means of removing subcutaneous fat.

Adipose Tissue↗

Liposuction and the platysma muscle.

Adequate correction of an obtuse cervicomental contour frequently requires not only fat removal but tightening of the platysma muscle as well. The introduction of liposuction as a safe and effective technique for removing subcutaneous fat and sculpturing the neck has created some confusion as to the need, if any, to manipulate the platysma muscle.

Adipose Tissue↗

Preliminary report on complications of the extended cervicofacial rhytidectomy.

The facelift is one of the major surgical procedures for facial rejuvenation. Over the years it has evolved from local skin excisions to wide undermining and manipulation of the subcutaneous layers. Presently, controversy exists concerning the extent of undermining. Minimal flap undermining is felt to give less than an optimum cosmetic result that in turn only lasts for a very short period of time, while more extensive procedures are thought to jeopardize the patient with increasing morbidity from associated complications. Since 1978, the author has been a strong proponent of the widely undermined facelift with concomitant excision and rotation of the subcutaneous layers. A review of the patients done since 1978, who had the more extensive operation, was undertaken to determine the incidence of postoperative complications. Even though the series is small, the results are encouraging.

Face↗

Pediatric vocal cord paralysis.

Pediatric vocal cord paralysis accounts for approximately 10% of all congenital laryngeal lesions. Early detection of these neurogenic disorders is based upon a high index of suspicion and is important to prevent catastrophes during periods of acute respiratory embarrassment. This paper reviews the symptoms, etiology and management of unilateral and bilateral vocal cord paralysis as it pertains to this age group. A case is presented of a neonate with vocal cord paralysis and associated hydrocephalous and meningomyelocele to illustrate many of the problems associated with pediatric laryngeal paralysis.

Abnormalities, Multiple↗

Hemifacial atrophy. A review of an unusual craniofacial deformity with a report of a case.

Progressive hemifacial atrophy is an unusual craniofacial deformity that is amenable to surgical reconstruction. The disease may involve any layer of the superficial facial tissues as well as cartilage and bone. While the cause of the disease is unknown, several hypotheses exist to account for the progressive nature of the disorder. Histologically, the skin undergoes thinning of the Malpighian stratum and atrophy of the skin adenexa and dermal units. The subcutaneous tissue shows chronic inflammatory changes. This picture closely resembles that of scleroderma, and some authors believe the disorder to be an isolated form of scleroderma. Various hypotheses have been promulgated as to the cause of this disorder, its pathologic process, and varied clinical presentation.

Adult↗

Tongue flap reconstruction in cancer of the oral cavity.

The mobility, size, and composition of the tongue make it ideal for oral cavity reconstruction following resection for carcinoma. The tongue flap provides a ready means of primary closure without increased morbidity, especially in patients who have had extensive therapeutic or preoperative irradiation treatment. The position of the tongue adjacent to the surgical defect and its excellent blood supply allow its nondelayed utilization. In most cases, use of the tongue flap precludes the necessity for multiple-staged reconstruction with regional pedicle flaps, with an improvement in functional results in terms of immediate healing, swallowing, and articulation over previous methods of reconstruction.

Carcinoma, Squamous Cell↗

Complications of dermal graft protection of carotid artery.

The efficacy of autogenous dermal grafts for carotid artery protection in head and neck surgery has been investigated experimentally and propounded clinically. A review of 194 dermal grafts from 1966 to 1972 at the otolaryngology service of Washington University Medical Center revealed two broad categories of complications that were unique to dermal graft protection of the carotid artery. Two cases of inclusion cysts that developed two years after implantation of the dermal graft were classified as a complication secondary to technical problems of taking the graft. The second category of complications arose as a result of epithelialization of the exposed dermal graft. While the overall incidence of complications that were attributable to the dermal graft was approximately 6%, autogenous dermis continues to provide an excellent method for carotid artery protection.

Carotid Arteries↗

Exteriorization of thoracic duct lymph. Theoretical considerations and an experimental model.

Successful manipulation of the immune response will ultimately provide the answers for controlling homograft rejection, reversing autoimmune states, and quite possibly for curing carcinoma and other malignant neoplasms. During the past decade, many new drugs and techniques have been developed that alter the immune state. The theoretical basis for approaching the immune system via the thoracic duct is based on the fact that 90% to 95% of the cells in thoracic duct lymph are thymus-derived lymphocytes. Therefore, by tapping the thoracic duct, we could conceivably manipulate the T lymphocytes and control the cell-mediated arm of the immune system. This has in fact been done in renal transplantation and autoimmune diseases. An experimental canine model was developed that exteriorized lymph flow in a closed system. We describe our experiences with four dogs and we discuss proposed immunologic manipulation.

Animals↗

Incidence, predisposing factors and outcome of pharyngocutaneous fistulas complicating head and neck cancer surgery.

A major complication of head and neck cancer surgery following radiation and extensive resection is pharyngocutaneous fistula. A retrospective analysis of 36 fistula patients out of 376 major head and neck procedures between January 1971 and July 1973 revealed certain guidelines for improved clinical management. Since a large discrepancy existed in the incidence of fistulas between the different surgical procedures, each operative group was examined separately. The incidence, predisposing factors, and methods of treatment for this complication following composite jaw-neck resections and various laryngeal procedures are analyzed and discussed.

Debridement↗

Povidone-iodine: an adjunct in the treatmen of wound infections, dehiscences, and fistulas in head and neck surgery.

Extensive research has been done to elucidate the cellular and biochemical events of a healing wound. Similarly, new techniques are continually being investigated which would stimulate and augment the reparative process. This paper describes the uses and biochemistry of povidone-iodine which has gained widespread acceptance as a surgical preparation. However, its use as a topical agent for treating head and neck wound infections, dehiscences, and salivary fistulas has gained little recognition. Povidone-iodine is a unique compound formed by binding free iodine to polyvinylpyrrolidone. Previously, the toxic effects of iodine limited its use to preparation of the skin for surgery. When bound to the pyrrolidine molecule, iodine becomes water soluble and markedly less toxic. As a result, the broad antimicrobial spectrum of iodine may be used topically to control wound sepsis. It can be applied to mucosal surfaces without producing burns. The brown color acts as an indicator of its clinical effectiveness. When the dressings become light yellow or pale, free iodine is no longer being released and the dressing should be changed. Povidone-iodine is not a panacea for correcting interruption in the healing process during the postoperative period. The basic management of wound infections, dehiscences, and fistulas remains unchanged. Incision and drainage, debridement and flap contracture, lateralization, and diversion are necessary to initiate the healing process. Familarity with each phase of healing provides the basis for managing each of these surgical problems. Topical povidone-iodine not only controls wound sepsis but augments wound healing. The physiologic correlation with each phase of wound healing for these various surgical problems is elaborated and clinical cases presented.

Administration, Topical↗