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Biomedical subjects

D D Haas

Publications and source records attributed to D D Haas.

5 recordsLinked to original sources

Temporal sequence study of the factors affecting corneal edema associated with soft contact lens wear.

The contribution of various factors to the edema associated with soft contact lens wear is considered. Time of wear, individual patient response level, baseline thickness of the cornea, and base curve radius of the contact lens are found by multiple regression analysis to be the most significant contributors to edema. The small but significant contribution of contact lens base curve to edema suggests that some oxygen is supplied to the cornea via a tear pump mechanism.

Contact Lenses, Hydrophilic↗

Electrophoretic mobilities and diffusion coefficients of hemoglobin at high pH.

Diffusion studies by photon correlation of scattered laser light confirm the dissociation of the tetrameric form of human carboxyhemoglobin to dimers above pH 10 and provide new estimates of the subunit dissociation equilibrium constants in this pH range. Electrophoretic light-scattering experiments under the same conditions reveal that the electrophoretic mobilities of tetramers and dimers are indistinguishable to within instrumental resolution (ca. 7% in these experiments). The data imply an increase of the electrical charge on the dimer of at least 2.8 to 4.4 net negative charges upon dissociation. Mechanisms for the accumulation of negative charge by the dimer upon dissociation of the tetramer are proposed.

Blood Protein Electrophoresis↗