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D D Hughes

Publications and source records attributed to D D Hughes.

6 recordsLinked to original sources

Evaluation of two spirometers: a comparative study of the Stead-Wells and the vitalograph spirometers.

The characterisitcs and performance of the Vitalograph dry spirometer were studied, and a direct comparison was made with the Stead-Wells spirometer, as recommended by the Committees on Environmental Health and Respiratory Physiology of the American College of Chest Physicians. The Vitalograph calibrates well against the Stead-Wells spirometer for measurements of vital capacity and forced expiratory volume in one second in normal subjects and in patients with various pulmonary conditions. Both spirometers failed to satisfy the committees' recommendations for resistance and inertia, the Stead-Wells showing the better values. Nevertheless, it is suggested that the Vitalograph is very suitable for the routine assessment of ventilatory function in the laboratory or in population surveys. Its light weight, portability, and robustness give it an added advantage.

Airway Resistance

IVE (Image Visualization Environment): a software platform for all three-dimensional microscopy applications.

IVE (Image Visualization Environment) is a software platform designed from the outset to handle all aspects of modern computerized multidimensional microscopy. This platform provides users with an execution environment in which 5D data (XYZ, wavelength, and time) can be easily manipulated for the purpose of data collection, processing, display, and analysis. During the entire process, powerful data display functions are readily available for extracting complicated three-dimensional information through data visualization. By employing both the shared memory and multitasking features of the UNIX operation system, individual functions can be implemented as separate programs, and multiple programs can access the same data pool simultaneously. This enables users to combine the functionalities of different programs to facilitate each unique data analysis task. Furthermore, by defining an appropriate program execution model, commonly shared functional components such as data display, data I/O and user interface, etc. can be implemented using simple IVE library calls. This dramatically reduces the program development time and ensures consistency throughout the entire software system. As a result, users can quickly master the microscopy software system and new functions can be easily integrated, as different functional requirements arise for different research projects.

Chromosomes

Determination of dimetridazole and ipronidazole in feeds at cross-contamination levels.

A rapid method for the determination of dimetridazole and ipronidazole in feeds is described. The compounds are extracted from a borate buffer (pH 8.65) with benzene, partitioned into 1N HCl, and then partitioned back into benzene from a basic aqueous phase. The benzene extract is concentrated and injected onto a nonpolar (Apiezon L) gas chromatographic column for determination by 63Ni electron-capture detection. Recoveries from feeds of various composition, spiked at 0.2 ppm with both dimetridazole and ipronidazole, ranged from 70 to 115%; for the same feeds spiked at 1 ppm or more, the recoveries were greater than 80%. Carbadox, furazolidone, levamisole, oxytetracycline, chlortetracycline, sulfamethazine, sulfaquinoxaline, arsanilic acid, piperazine, penicillin, and commonly added vitamins and minerals do not interfere. A 2-dimensional thin layer chromatographic system is presented as a means of additional identification.

Animal Feed