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Biomedical subjects

D D Kulpati

Publications and source records attributed to D D Kulpati.

At least 19 recordsLinked to original sources

Colonic immunity in patients and amoebic liver abscess.

Secretory immunoglobulin A (S-IgA), coproantibody titre (antiamoebic) and IgA, IgG, IgM immunocytes in rectal mucosa were studied in 13 patients with amoebic liver abscess (ALA) prior to and 4-6 weeks after completion of antiamoebic therapy. Ten asymptomatic Entamoeba histolytica cyst passers and 17 healthy age and sex matched volunteers served as controls. Fecal S-IgA levels and counts of IgA bearing immunocytes in mucosa were significantly higher in patients with ALA and cyst passers as compared to healthy controls and showed a significant fall after treatment. Fecal antiamoebic antibodies were high in cyst passers and in cases of ALA after treatment. Raised levels of S-IgA and IgA class immunocyte counts probably indicate a local mucosal immune response directed at containing the infection.

Antibodies, Protozoan

Lasers in pulmonology.

Lasers have multiple applications in pulmonary medicine. The Nd: Yag laser is at present widely accepted for the management of respiratory problems. The major indications are central tracheobronchial obstruction due to neoplasms, uncontrolled haemorrhage from malignant lesions and tracheal stenosis. Its role is entirely palliative and only occasionally curative. Two main complications are perforation and bleeding. The basic concepts, techniques and use in various respiratory problems are discussed.

Bronchial Neoplasms

Dot immunobinding assay versus sandwich ELISA in diagnosis of invasive amoebiasis.

Sera from 34 patients of amoebic liver abscess (ALA) and 11 patients with amoebic dysentery (AD) were examined for the presence of specific Entamoeba histolytica (EH) antibodies and amoebic antigen by enzyme linked immunosorbent assay (ELISA) and dot immunobinding assay (DIB). Both techniques were found to be equally sensitive for detecting antiamoebic antibodies (89.5 and 91.9% respectively) and highly specific (100%) in patients of ALA. ELISA was found to be more sensitive (94.4%) in detecting circulating amoebic antigen compared to DIB (68%) in patients of ALA. Specific antibodies, in significant levels, were detected in 3 and 5 patients of AD by ELISA and DIB assay, respectively. As DIB assay is easier to perform and less expensive, is recommended for detection of antibodies in patients with invasive amoebiasis.

Animals

Ewing's tumour of rib presenting as chest mass.

A case of Ewing's tumour of rib presenting as chest mass is reported. The role of computed tomography and chest ultrasound in evaluating such patients is discussed along with a brief review of literature.

Adult