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Biomedical subjects

D D Maglinte

Publications and source records attributed to D D Maglinte.

At least 91 records · Page 5Linked to original sources

Eosinophilic enteritis associated with chronic eosinophilic pneumonia.

A case of eosinophilic pneumonia and eosinophilic infiltration of the small bowel and colon is reported. The patient presented with nonspecific chest and abdominal symptoms, and lack of response to therapy for presumed pneumonia. Further investigation including lung, muscle, and gastrointestinal tract biopsies revealed eosinophilic infiltration of the lung and gastrointestinal tract, an association that does not appear to have been previously documented.

Adult↗

Enteroclysis in the diagnosis of chronic unexplained gastrointestinal bleeding.

In a six-year period (1977-83), lesions were identified by enteroclysis in 26 patients with melena or recurrent gastrointestinal bleeding undiagnosed by other modalities. These included nine Meckel's diverticula, three metastatic lesions, three primary carcinomas, one lipoma, four leiomyomas, five surgically created blind pouches, one carcinoid, and one idiopathic dilatation of the ileum. Our experience suggests that, when the standard diagnostic procedures used to investigate chronic gastrointestinal blood loss are unrevealing, enteroclysis should be performed. The method is fast, accurate, is done in one sitting, and can be productive in the diagnostically difficult patient.

Adenocarcinoma↗

Blunt chest trauma and suspected aortic rupture: reliability of chest radiograph findings.

The chest radiographs of 86 patients with suspected aortic rupture from blunt chest trauma were reviewed. Seventy-three patients had no evidence of aortic rupture on aortography or surgical exploration, and 13 patients had surgically confirmed rupture. Sixteen radiographic findings were analyzed for sensitivity and specificity in detecting aortic rupture. The following findings were not statistically significant: hemothorax on either side; rib fractures on either side; pneumothorax on either side; lung contusion; widened left paravertebral stripe; and widening of the mediastinum, along with an increased ratio of mediastinal width to chest width. The most helpful findings leading to suspicion of aortic rupture included nasogastric tube or tracheal deviation to the right at the T4 level; depression of the left mainstem bronchus; and loss of the aortic contour or knob and left apical cap. False positives and false negatives occurred with each radiographic sign, indicating that there is no single finding that is absolutely reliable in predicting or excluding significant injury in every patient with suspected aortic rupture. Analysis of combinations of findings found that when the aortic contour and knob are normal and the nasogastric tube and trachea are not deviated, there was no case of aortic rupture in four consecutive years of experience. These four signs can be used to exclude aortic rupture.

Aortic Rupture↗

Clinical application of in vitro studies for barium-enema examination following colorectal biopsy.

A total of 150 colorectal biopsies were performed in 71 patients and correlated with the barium-enema examination (BE). The investigation was divided into two parts. In the first part, involving 19 patients, the depth of each biopsy specimen was determined histologically prior to BE and potential complications related to the biopsy-BE sequence were evaluated. In the second part, involving all 71 patients, the depth of biopsy specimens taken from various colon lesions was determined histologically without regard to the timing of BE. The results confirm previous in vitro findings in pigs and dogs, namely: (a) BE may be performed without delay following a superficial biopsy, but should not be performed until at least 6 days after a deep biopsy; (b) transcolonoscopic biopsies are likely to be superficial, while transproctoscopic biopsies have the potential to be deep; and (c) BE should be delayed at least 6 days following polypectomy or polyp biopsy performed with electrosurgery.

Barium Sulfate↗

Flow artifacts in double-contrast esophagography.

Artifacts related to barium flow during double-contrast esophagography may obscure mucosal surface details. Double-contrast esophagograms with flow artifacts of 35 patients were evaluated to determine the effect on radiographic interpretation and to assess the method of examination. Initial radiographs obtained during swallowing of barium were compared with those obtained after a slight delay while patients repeatedly dry swallowed. When severe surface flow artifacts were present, the extent of mucosal disease was underestimated in all cases. Mild surface flow artifacts interfered with the demonstration of the reticular pattern of Barrett esophagus, and luminal flow artifacts caused misinterpretation. The demonstration of strictures was unaffected by flow artifacts. This study suggests that the dry swallowing maneuver and some delay improve depiction of esophageal surface details on double-contrast radiographs and obviate interpretive error from barium flow artifacts.

Barium Sulfate↗

Plain-film criteria for excluding aortic rupture in blunt chest trauma.

Emergency room supine chest films of 86 consecutive patients with blunt chest trauma and possible aortic rupture were reviewed. Sixteen radiographic signs were analyzed independently and in combination. Only two signs associated with aortic rupture were statistically significant: deviation of the nasogastric tube to the right at the T4 level and depression of the left main-stem bronchus below 40 degrees from the horizontal. False positives and false negatives occurred with each individual radiographic sign. However, if the aortic knob and contour appeared normal and the trachea and nasogastric tube were not deviated, no case was found of aortic rupture in 4 consecutive years of experience. These four signs can be used to exclude the diagnosis of aortic rupture in patients with blunt chest trauma.

Aorta, Thoracic↗

Current perspectives in colon radiography: the postendoscopy and postbiopsy barium enema.

Controversy prevails regarding the same-day performance of barium enema examinations and endoscopy. Concerns focus upon the diagnostic quality of the postendoscopy barium enema and the risk of perforation if colorectal biopsy is performed during the endoscopy. Results of a study of 295 patients support that rigid or fiberoptic sigmoidoscopy can be performed the same day as single- or double-contrast barium enemas without adversely affecting the quality or interpretation of the barium examination. Animal studies suggest that a barium enema may be performed safely immediately after a superficial biopsy of a nondiseased colon and 6 days after a deep biopsy. Barium sulfate appears to have no deleterious effect on the healing of colorectal biopsy sites. These findings have important implications when considering health care logistics and cost containment.

Barium Sulfate↗

Lymphomatous esophageal nodules: the difficulty in radiological differential diagnosis.

A case of lymphomatous infiltration of the esophagus presenting as diffuse nodularity on double contrast esophagography is presented. This report is a reminder to the radiologist and clinician of the varied roentgen manifestations of many entities involving the esophagus in the immunocompromised patient and the difficulty in radiological differential diagnosis.

Aged↗

Leiomyoma in a "blind pouch".

This report describes a patient with anemia and chronic diarrhea secondary to an ulcerating leiomyoma in a blind pouch. It emphasizes the clinical and radiologic difficulty in diagnosing focal lesions of the mesenteric small bowel and the need for a careful scrutiny of all segments of small bowel in a patient with unexplained anemia and diarrhea.

Adult↗

Detection of surgical lesions of the small bowel by enteroclysis.

Enteroclysis is an examination in which barium is infused directly into the small intestine, and compression radiographs are taken on each segment. This method eliminates many of the inherent limitations of the conventional small bowel follow-through examination. This report concerns 45 patients with 48 small bowel lesions. They were missed on the conventional examination but detected within 3 months by subsequent enteroclysis and confirmed surgically. There were 15 patients with Meckel's diverticula, 7 with obstructive adhesive bands, 5 with Crohn's disease, 5 with blind pouch syndrome (1 with a leiomyoma inside the blind pouch), 2 with other leiomyomas, 3 with metastatic carcinoma, two with primary carcinoma 3 with radiation stricture, two with sinus tract lesions and fistulas, and 1 with another lesion. Improved intubation techniques and better barium mixtures make enteroclysis possible in most hospitals. As surgeons appreciate the value of enteroclysis, they can request this examination for appropriate patients to sooner find many surgical lesions of the small bowel which frequently go undiagnosed.

Adult↗

Enteroclysis in partial small bowel obstruction.

In a 5 year period, 56 patients with suspected partial small bowel obstruction were evaluated by enteroclysis or the antegrade small bowel enema. Mechanical partial obstruction was diagnosed by enteroclysis in 38 of the patients, 24 of whom required surgery. The diagnosis by enteroclysis was confirmed in 23 of the patients. In the single patient with "false-positive" enteroclysis, the obstruction had been interpreted as minimal. The thirteen remaining patients were managed conservatively. The possibility of significant mechanical obstruction was excluded by enteroclysis in 19 patients. There were no complications associated with the procedure. Enteroclysis is a safe, rapid, and accurate method for the evaluation of patients with partial small bowel obstruction.

Barium Sulfate↗

A comparison of pumps used for enteroclysis.

An electric motor-driven pump for enteroclysis is more efficient than a hand-operated pump. It allows the radiologist to monitor infusion flow rates, protects the technologist from scattered radiation, reduces manpower, is associated with fewer mechanical problems, and improves uniformity of flow during performance of the procedure.

Barium Sulfate↗

Mediastinal-width/chest-width ratio in blunt chest trauma: a reappraisal.

The chest radiographs of 54 patients with blunt chest trauma and suspected aortic rupture were reviewed retrospectively. A mediastinal-width/chest-width ratio was calculated at the level of the aortic arch. There were 44 patients without evidence of aortic rupture on aortography or surgical exploration and 10 patients with surgically confirmed aortic rupture. There was no identifiable ratio of significance in distinguishing those with aortic rupture and those without rupture. The mediastinal-width/chest-width ratio is of insufficient sensitivity and specificity in confirming or excluding aortic rupture to be clinically useful.

Adult↗