Tumour-cell killing by X-rays and immunity quantitated in a mouse model system.
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Biomedical subjects
Publications and source records attributed to D D Porteous.
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A simple and inexpensive unit for the collection of excreta from individual mice was designed. The results of experiments in which counts of collected radioactive excreta were made closely approximated those previously obtained using a whole-body gamma counter.
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The toxicity of the low-energy electrons from (125)I in labelled IUdR was assayed by labelling the DNA of BP8 mouse tumour cells with the nucleoside and studying their subsequent growth in culture. Toxicity was observed in cells grown in medium containing more than 0·01 μCi/ml. The amount of label incorporated into cells showing deleterious effects is compared with that reported by others.
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