PubMed Health⌕ Search

Biomedical subjects

D Dargent

Publications and source records attributed to D Dargent.

At least 127 records · Page 7Linked to original sources
PubMed1976

[Difficulties in the detection and the diagnosis of carcinoma in situ of the uterine cervix in the presence of associated dysplasia].

Ninety nine cases of carcinoma in situ of the cervix are reported. In all cases, the definitive diagnosis was established after study of an operative specimen (cone biopsy or hysterectomy) examined by serial section. Pre-operative cytology was falsely negative (or suggestive of simple dysplasia) in 35,4 per cent of cases and pre-operative biopsy falsely negative in 40 per cent. These errors were approximately twice as common in cases in which dysplasia was present in association with the caricinoma (40 cases) than in those cases in which the malignancy alone was present (59 cases). The practical conclusions which may be drawn from these findings in relation to detection and diagnosis are discussed.

Adult↗
PubMed1976

[Histometric study of 55 cases of carcinoma in situ and microinvasive carcinoma of the cervix. Histogenetic deductions].

The authors present the results of a quantitative study of carcinoma-in-situ and occult invasive cancers of the cervix. 40 separate carcinomata in-situ were measured and the limits of their topography precisely defined with reference to the external os on the one hand and the "last gland" on the other. It is known that this gland is situated at the site of the original junction between the cylindrical and pavement epithelia. It confirms that carcinoma-in-situ always (with few exceptions) develops upwards from the area of the original junction between the cylindrical and pavement epithelia, and its topography is higher than that of dysplasia especially when the two types of lesion are associated.

Adult↗