Biomedical subjects

D De Weert

Publications and source records attributed to D De Weert.

3 recordsLinked to original sources

PubMed1990

Predictive value of two endogenicity measures.

Endogenicity has been considered to have a major predictive value as to the therapeutic response to antidepressants. Two recently introduced measures of endogenicity (the Michigan Discriminant Index and the Hamilton Endogenomorphy Subscale) were investigated regarding their potential predictive value. It was concluded that, in a group of selected depressive patients, neither the Michigan Discriminant Index, nor the Hamilton Endogenomorphy Subscale, had a predictive value concerning short-term response to antidepressants.

Adult↗

PubMedDate not supplied

Primary versus secondary depression. A psychometric approach. Preliminary results.

Differences between primary and secondary depression have been studied from different viewpoints. This study aimed at determining a possible difference in terms of personality factors and psychodynamic variables. Two psychological tests (the MMPI and the Gottschalk-Gleser) were administered to 32 depressed inpatients, diagnosed according to Feighner criteria. A statistically significant difference was found only for the Psychasthenia scale on the MMPI. However a discriminant analysis using the MMPI results yielded approximately 80% correct classification. The Gottschalk-Gleser test did not provide any significant difference.

Depressive Disorder↗

PubMedDate not supplied

The correlation of dexamethasone suppression test and thyrotropin-releasing hormone test results in different subtypes of depression.

TSH response to I.V. TRH and suppression of cortisol secretion by dexamethasone were studied in 51 depressive inpatients. There was no significant relationship between the results on both tests, considering blunted TSH responses to TRH and nonsuppression on the DST. Both tests were not complementary in identifying various subgroups of depression as far as the predictive value of a positive result on either or both tests is concerned. Methodological and clinical issues regarding these markers are briefly discussed.

Adult↗