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Biomedical subjects

D Debiasi

Publications and source records attributed to D Debiasi.

18 recordsLinked to original sources
PubMed1993

Relationship between epidermal growth factor receptor and other prognostic factors in gynecological cancers.

In 62 cases of gynecological malignancies, 16 of the ovarian, 31 of the endometrium and 15 of the cervix, the EGF-R status was evaluated in order to establish its prognostic value and its correlation with other classical prognostic factors. We have failed to demonstrate any correlation between EGF-R status and stage, grade and hormonal receptors, ER/PgR, in ovarian and cervical cancer. In contrast, in endometrial cancer, we observed significantly lower levels of EGF-R in poorly differentiated tumors. Moreover, a weak negative relationship between EGF-R and PgR status was found. Regarding survival, we noticed a better prognosis in patients with ovarian cancer EGF-R positive, but without statistical significance.

Adult↗
PubMed1982

Estetrol and utero-placental flow after progesterone load.

On the basis of recent demonstration in animals of the effect of some hormones on uteroplacental flow, the Authors examined the response of plasmatic Estetrol (15 alpha-hydroxy-estriol) after the administration of progesterone to pregnant women with low Estrogen values. The increase of this compound was related to an improvement of placental function, probably dependent on an increase of available O2, and therefore on uterine blood flow. This can justify a progesterone treatment in such pregnancies.

Estetrol↗
PubMed1982

Unconjugated estetrol in normal pregnancy.

The Authors studied the levels of Estetrol (15 alpha-hydroxyestriol) in the amniotic fluid, in maternal and foetal plasma, by the RIA method, in near-term pregnancies. Higher concentrations of this steroid were found in the foetal plasma and in amniotic fluid than in the maternal plasma. These data, even though of little clinical importance, confirm the foetal origin of this compound and suggest further studies, especially in the amniotic compartment.

Amniotic Fluid↗
PubMed1980

[Intrahepatic cholestasis and fetal prognosis (author's transl)].

The Authors have executed a retrospective study about the incidence of intrahepatic cholestasis in pregnancy in 85 patients hospitalized in the department of Obstetrics and Gynaecology, University of Parma. Particularly, they have investigated about the incidence of fetal distress, about the intrauterine death, and about poor intrauterine fetal growth.

Cholestasis, Intrahepatic↗