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Biomedical subjects

D Dehesdin

Publications and source records attributed to D Dehesdin.

At least 19 recordsLinked to original sources
PubMed1992

[Caustic stenoses of the esophagus].

Oesophageal stenosis is a frequent complication of caustic burns, especially when deep injuries are present, due to the presence of scar tissue. After the treatment of initial complications and after an initial endoscopic evaluation, a few preventive measures can be decided to protect the upper part of the gastrointestinal tract. These measures include complete parenteral nutrition for some, and calibrating nasogastric tube for others; corticosteroid treatment is discussed. When stenosis is present, endoscopic dilatations can be performed. If they failed or instead of them, surgical replacement can be proposed with gastro or coloplasty. Resection of burned oesophagus prevents the risk of mucocele or cancer.

Burns, Chemical↗
PubMed1992

[Metastasizing pleomorphic adenoma].

A case of metastasizing pleomorphic adenoma is reported with a review of the literature. It's a enigmatic lesion of the parotid gland in with both the primary tumor and metastasis were composed of benign pleomorphic structures. We think that some intra or extra cellular factors mut be discovered to recognize the malignant potential of this tumors and further to understand all cancerous pathology.

Adenoma, Pleomorphic↗
PubMed1992

[Management of caustic burns of the esophagus in children].

The authors describe their therapeutic approach to caustic burns of the esophagus in pediatric patients. Initially, early endoscopic evaluation is carried out under general anesthesia using a stiff tube then a fiberoptic endoscope. During this procedure, severity of esophageal damage is determined: stage I: mild burn requiring no treatment; stages II and III: severe burn with a risk of subsequent esophageal stricture requiring insertion of a nasogastric stent. A repeat endoscopy is performed after approximately 25 days to evaluate healing. If healing has occurred, the nasogastric tube is removed and dynamic esophagography is performed 2 to 7 days later. Patients with strictures should be treated with repeated endoscopic dilatation at gradually increasing intervals. Surgery is indicated only in patients with complications or multiple strictures after failure of dilatation; trans-mediastinal colon esophagoplasty with removal of the burned esophagus is the method of choice.

Burns, Chemical↗
PubMed1991

[Ingestion of caustics by children. Report of 23 deep lesions. Therapeutic attitude and long-term results].

In children, 23 caustic injuries of oesophagus with deep lesions (second or third degree of burn) were treated in pediatric ENT department (Pr ANDRIEU--Rouen) during a 19 years long period. Endoscopy in emergency, nasogastric tube for stent and repeated dilatations were the bases of the treatment. 14 second degree burns and 7 third degree burns were complicated of 9 stenosis and one death. The mean duration of total treatment was 43 months. The mean number of dilatations was 38 months. 4 stenosis were definitely cured. 8 children had normal feeding. Mean following was 8 years with good long term results.

Attitude of Health Personnel↗
PubMed1990

[Comparative experimental study of nerve repairs by classical suture or biological adhesive].

The respective possibilities of nerve reparation with classical microsutures or biological glue (bioglue) were compared on experimental rat sciatic nerve lesions. Seventy rats were operated upon, and 69 results can be interpreted. 22 had a microsuture, 47 anastomosis with bioglue (Tissucol). The animals were followed for 120 days, and the results assessed on muscular testing, electrostimulation, optic microscopic histology, and morphometry. Five anastomosis dysjunctions occurred in the bioglue group, because of technical errors. All other animals improved from the 60th day. From the histological view point, the results with bioglue were more satisfactory, because of the absence of foreign body reaction to sutures; the authors conclude that because of the equivalent results on nerve function, and better histological results with bioglue, its use is preferable to repair nerves, especially when microsuture is technically difficult.

Animals↗
PubMed1990

[Melanoma of the nasal fossae and sinuses, apropos of a series of 7 cases].

The authors present their experience of the malignant, mucosal melanomas involving the nasal cavity and paranasal sinuses through a retrospective study of 7 cases, observed in Rouen from 1977 to 1988. The results are compared to a review of world literature. The mucosal melanoma of the nose and sinus is a rare entity, representing approximatively 40 per cent of all sinonasal neoplasias. The signs and symptoms of sinonasal melanomas are non-specific. Therefore, the diagnosis is often delayed. The histological diagnosis is difficult given the substantial polymorphism of these tumors and the experience of achromatous forms. Electron microscope study and immuno-histo-chemical techniques using various monoclonal antibodies make it possible to eliminate the other major, differential diagnoses. Surgery is the primary method of treatment, sometimes combined with adjunctive postoperative radiotherapy. More recently, combined treatment with interferon and cimetidine appears to be interesting. The prognosis is very poor, if compared to skin melanomas, with a five year survival rate of 5 to 30 per cent. Local recurrence at the primary site and distant metastases are the most common caused of treatment failure.

Aged↗
PubMed1989

Selective reinnervation of the abductor and adductor muscles of the canine larynx after recurrent nerve paralysis.

Functional rehabilitation of the larynx after unilateral vocal cord paralysis was attempted in the dog by selective reinnervation of the laryngeal muscles. The intralaryngeal branches of the right recurrent nerve were dissected. The adductor branch was anastomosed with the ansa cervicalis; the abductor branch was anastomosed with the trunk of the phrenic nerve either within the larynx or through the recurrent nerve, the adductor branch of which was sectioned. Results could be analyzed in seven dogs: mobility of the vocal cord was checked, and electromyography, stimulation of the nerves, and histologic studies were performed. Functional reinnervation of both the adductor and abductor muscles was obtained in only one case, with good abduction. Adduction was recorded in five cases. False-positive results emphasize the necessity of collecting several types of data before concluding that functional reinnervation has been accomplished. The reliability of the procedure can and must be improved.

Anastomosis, Surgical↗
PubMed1989

[Role of the septal cartilage in facial growth. Experimental study in rats].

The authors report a surgical experiment on nasal septal cartilage in the growing rat. Three different operations performed on 95 animals to assess. The role of septal cartilage in facial growth and the effects of standard surgical techniques on facial growth. The results obtained show that sub-periosteal dissection of the nasal bones has no adverse effect on facial growth; conservative procedures such as removal and replacement of septal cartilage, produce minimal effects on facial growth, but large septal cartilage excision obviously impairs facial growth. Guidelines concerning septal surgery in children are suggested in view of these results.

Animals↗
PubMed1988

[Dura mater healing after repair with aponeurotic plasty. Comparison of results between classical sutures and fibrin adhesive glue. Fibrin adhesive in frontobasal injuries. An experimental study].

The aim of the present experimental study was to compare the quality of the healing obtained with fibrin glue or with classical sutures to repair post-traumatic fronto-basal fistulae. The anterior part of the cranial base and a piece of dura mater are removed. The first group of rabbits (n = 26) is repaired with fibrin glue; the second group with separate sutures. The postoperative controls are realised by injection of 1 ml patent blue in the cisterna magna to detect C.S.F. rhinorrhea, x-ray study of the cranial bases and histological samples of transversal slices of the cranial base. The different biological findings seem to be important arguments to confirm the useability and trustworthiness of human origin fibrin glues to close meningeal wounds.

Animals↗
PubMed1988

[Recurrent laterocervical suppurations. Role of fistulae and cysts of the 4th branchial pouch].

Four cases of fistula of fourth branchial pouch are used as a basis for a description of the two possible clinical pictures: left cervical suppuration in a neonate with respiratory distress or recurrent cervical cellulitis in an older child or young adult usually diagnosed as a suppurative thyroiditis. Diagnostic features are outlined and emphasis placed on the need for an adapted surgical excision originating at the pharyngeal orifice of the fistula. In two of the four cases reported its trajectory was between muscle and mucosa planes and then in contact with the cricothyroid joint as a small cord, otherwise unidentifiable.

Adolescent↗
PubMed1986

Unilateral congenital choanal atresia and maxillary sinus development.

Most authors feel that the maxillary sinus and dento-alveolar arch do not develop normally in case of choanal atresia. This as explained by respiratory deficiency on the atretic side. A series of 11 cases of unilateral choanal atresia, either untreated or treated after the period of maximum growth, have been studied by clinical examination, serial X-rays and cephalometric tracings in order to compare atretic and normal sides. No significant difference has been found, neither for size nor shape of the maxillary sinus. These observations are therefore in contradiction to earlier reported findings and require further study.

Adolescent↗
PubMed1985

[Deafness and autoimmunity].

The etiology of a perception deafness cannot be determined in most cases. The autoimmune origin of some of them appears now to be increasingly possible, particularly when they form part of a disease affecting multiple systems. Three cases of this type are presented in an attempt, by analogy, to define the pathogenicity and criteria of the isolated "dysimmune" audiovestibular manifestations.

Autoantibodies↗
PubMed1985

[Benign sub-periosteal osteoblastoma of the nasal cavity. histological and ultrastructural study of a case].

A case of periosteal benign osteoblastoma arising in the left nasal cavity is presented. The tumor develops on the surface of the middle turbinate without evidence of bone destruction. It has been locally excised and has not recurred in 3 1/2 years. The histological aspect is identical to that of the other cases of genuine osteoblastoma. The ultrastructure (the first of a periosteal osteoblastoma) is described. The osteoblasts resemble normal osteoblasts with a few exceptions: irregular nuclei, abundance of well-developed rough-surfaced endoplasmic reticulum and numerous fine filaments. The osteocytes and osteoclasts basically resemble their normal counterparts. The final diagnosis of benign osteoblastoma rests at the light microscopy level. The differential diagnosis are reviewed. Distinguishing histologic and ultrastructural characteristics between this tumor and other benign osteoblastic tumors are discussed.

Cell Nucleus↗