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Biomedical subjects

D Devictor

Publications and source records attributed to D Devictor.

At least 109 records · Page 6Linked to original sources
PubMed1985

[Status epilepticus in the infant. Semeiologic, etiologic and prognostic aspects].

During a 4 year period, 79 infants aged from 1 month to 2 years suffered a status epilepticus (SE). The seizures were most often either generalized of tonic-clonic or clonic type, or unilateral clonic; they lasted or were repeated with persistent unconsciousness between the seizures for periods ranging from 30 min to several days. All the cases of SE lasting over 6 h resulted from a recognizable acute brain injury, whereas 11 of 14 cases lasting 1 h or less were cryptogenic. In 2 cases only, the neurological status was worse after the status, apparently as a result of the seizures themselves. The authors discuss the hypothesis of purely febrile HH syndrome and point out the importance of detailed clinical ictal and interictal characteristics for the etiological approach.

Child, Preschool↗
PubMed1985

[Respiratory function during wakefulness and sleep in a 7-year-old child with congenital alveolar hypoventilation of central origin].

Pulmonary function tests were performed in a 7 year-old girl with central alveolar hypoventilation syndrome treated with mechanical ventilation during sleep. Results showed: 1. during wakefulness decrease in residual functional capacity, in dynamic lung compliance and in lung transfer factor for CO; 2. during sleep the characteristics of the syndrome as reported in the neonatal period i.e. central alveolar hypoventilation in stages 2 and 3-4 which justified maintenance of mechanical ventilation when asleep.

Child↗
PubMed1985

[Water intoxication in children. Apropos of 2 cases].

The authors report 2 cases of water intoxication. These clinical cases show the importance of neurological signs during the acute period. Hyponatremia is constant and responsible for the clinical signs. A rapid treatment is necessary.

Adolescent↗
PubMed1984

Lung functional follow-up in children after severe viral infection.

Pulmonary function tests (PFT) were performed in 12 children after viral infection (VI) due to an adenovirus in 9 cases and occurring before the age of 4 in 10. Functional residual capacity (FRC), thoracic gas volume (TGV), total lung resistance (R1), dynamic lung compliance (C1dyn), expiratory flows and blood gases were measured during three periods after VI: from 3 to 12 months (n = 10), from 1 yr 6 months to 3 yr 8 months (n = 8), and from 4 yr 7 months to 8 yr (n = 6). In the short term period one child had normal PFT, while in the remaining cases there was increased R1, decreased C1dyn and hypoxemia. R1, C1dyn and blood gases did not significantly change between short and mid term periods. In the long term period the children had overinflation with trapped gases, airways obstruction and hypoxemia. These functional sequelae may be related to structural lesions due to VI and abnormal postnatal lung growth.

Adolescent↗
PubMed1984

[Evolution of the mortality rate of newborn infants transferred to a Parisian intensive care service from 1969 to 1978].

This study reports on the trend in neonatal death rates in a Paris intensive care unit between 1969 and 1978. Three time-periods were compared: 1969-1971, 1972-1974, and 1975-1978. These limits were chosen to take into account the introduction of continuous airway positive pressure in the unit in 1972, and the gradual implementation, from 1972 onwards, of a new perinatal care policy in France. The mortality rate was significantly lower in the second period than in the first, after adjustment on birthweight and type of disease. This trend varied according to type of disease: the death decreased significantly in case of membrane disease or foetal distress, but not in case of admission for amniotic inhalation or congenital anomalies. The gradual improvement in newborn's condition on arrival in the unit played a part in the improvement in survival, as well as the use of the continuous airway positive pressure.

Critical Care↗
PubMed1983

[Microbiological diagnosis of epiglottitis].

Forty patients, between July 1977 and April 1982, with clinical diagnosis of epiglottitis were studied for the presence of capsular antigen by counter-immunoelectrophoresis (CIE) and for positive blood culture. Blood culture was positive, for Haemophilus influenzae only, in 15 patients. Haemophilus influenzae type b antigen was present in blood and/or urine of 25 patients (blood 14 patients, urine 18 patients). CIE associated with blood culture give conclusive proofs of Haemophilus influenzae etiology in 30 patients.

Antigens, Bacterial↗
PubMed1983

[Microbiological diagnosis of epiglottitis].

Forty patients, between July 1977 and April 1982, with clinical diagnosis of epiglottitis were studied for the presence of capsular antigen by counter-immunoelectrophoresis (CIE) and for positive blood culture. Blood culture was positive for Haemophilus influenzae only, in 15 patients. Haemophilus influenzae type b antigen was present in blood and/or urine of 25 patients (blood 14 patients, urine 18 patients). CIE associated with blood culture give conclusive proofs of Haemophilus influenzae etiology in 30 patients.

Antigens, Bacterial↗
PubMed1982

[Electroencephalographic aspects and thiopental in 4 cases of severe pneumococcal meningitis in children].

We present an electroclinical study of 4 severe pneumococcal meningitis cases with intracranial hypertension. In addition to classical anticerebral edema therapy thiopental infusion was used. The plasma thiopental level seems to be only an incomplete indicator of cerebral drug effect, but must be measured to avoid accumulation. EEG monitoring appears to be better in evaluating the clinical status and barbituric impregnation. The burst suppression in EEG recording is noted at variable periods (9-48 h) after the start of the treatment and disappears on discontinuation of infusion while the plasma drug levels remain high. Further, in two cases EEG changes preceded clinical deficits. Evolution of clinical and EEG status was good in the 4 children.

Child↗
PubMed1982

[Immunologic study of familial lymphohistiocytosis. Eight new case reports (author's transl)].

We report 8 cases of familial lymphohistiocytosis collected in 6 families. Several data argue for an hyperactivation of the reticuloendothelial system (RES). An abnormal visualization of all organs was observed in a scintigraphic study after 99technetium labelled red blood cells injection. Blood monocytes contained very low peroxidase activity as detected by cytoenzymology and secreted large quantities of prostaglandin E2 (PGE2). Adherent cells isolated from blood exercised a strong suppressor effect on the proliferation of normal lymphocytes induced by phytohemaglutinin. This effect was reduced by indomethacin and therefore appears PGE2-dependent. One patient's serum exerced an inhibitory activity on antigen-induced proliferation of normal lymphocytes and on mixed leucocyte reaction. In contrast, cellular and humoral functions were not deeply impaired. The hyperactivation of the RES remains unexplained and not related to a graft versus host reaction, which could be excluded in 3 of our patients. Therapeutic attempts were not efficient, all patients dying despite steroid, vincaleucoblastin and indomethacin therapy.

Female↗
PubMed1982

[Perioperative management of 98 cases of type C esophageal atresia (1970-1980) ].

We report our experience about 98 cases of type C esophageal atresia admitted to our unit from 1970 to 1980. 78.6% underwent successful anastomosis; 65.3% were considered at high risk because of delayed diagnosis (34.6%), low weight (22.4%) or associated malformations (15.3%). These latest two were especially responsible for mortality. Our results are encouraging and stress the need for a high quality of surgical management, for a systematic detection of this malformation and for a delayed surgical procedure allowing a better preoperative care.

Esophageal Atresia↗
PubMedDate not supplied

[Subfulminant hepatitis A treated by hepatic transplant].

A case of subfulminant hepatitis A in a 3 1/2 year-old boy is reported. This child is alive after a liver transplantation. Such a procedure should modify the prognosis of severe hepatic failure whatever its origin, viral or toxic. Some practical problems concerning this new management of fulminant hepatitis are considered.

Child, Preschool↗
PubMedDate not supplied

[Hemodynamic effects of dobutamine in asphyxiated newborn infants].

The hemodynamic effects of dobutamine were studied by non invasive techniques in 6 full term neonates with severe perinatal asphyxia. At 10 micrograms/kg/min, dobutamine significantly increased the cardiac output, the heart rate and the aortic blood flow velocity. The mean arterial pressure increased but not significantly and the stroke volume remained unchanged. These changes seem to be dose dependent. The increase of cardiac output may be due to a chronotropic and inotropic effect of dobutamine. Dobutamine seems to be an effective agent for the treatment of low cardiac output in asphyxiated neonates.

Asphyxia Neonatorum↗