[Hepatic hydatidosis in West Africa. Association with peritoneal carcinomatosis].
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Adenocarcinoma↗
Biomedical subjects
D Diallo
Publications and source records attributed to D Diallo.
[Hepatic amebiasis. Reversible bilio-pancreatic changes].
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Gallbladder Diseases↗
Prevalence of antibodies against respiratory viruses in children of Koulikoro (Mali).
The prevalence of antibodies to viruses associated with respiratory illnesses (influenza, corona, R.S., adeno, parainfluenza Mycoplasma pneumoniae) has been investigated in 119 children under 3 years of age (Koulikoro region Mali) and 50 persons 15-19 years of age (Bamako/Mali). In the surveillance period (March 1982-September 1982) an outbreak of respiratory disease in association with RS virus took place. A rise of CF titer has been found in 90.8% of the children; 59.1% of them presented a fourfold or greater increase of titer. The GMT values rose from 1:7 to 1:48. Concerning influenza viruses a higher incidence of positive reactions has been observed only for H3N2 viruses. A fourfold CF rise of titer has been observed for adenovirus and mycoplasma pneumoniae in 3 cases each, for parainfluenza type I and III in 2 cases each, and for parainfluenza II in 1 case. In persons 15-19 years of age the incidence of positive CF reactions was relatively high (68%-98%), but the GMT values were moderate (1:12-1:25). These data confirm that the frequency of viral respiratory diseases is the same in tropical countries as in countries with a temperate climate.
Adenoviruses, Human↗
[Serum conversion rate following oral poliomyelitis immunization in Mali, Africa 1982].
118 infants under 3 years of age were thrice orally immunised against poliomyelitis at 2 months interval. Before the vaccination 26% were triple negative and 24% triple positive. 44% had neutralising polio antibodies type 1, 53% type 2 and 52% type 3. At the end of the vaccinations 59% of the vaccinees were triple positive and only 3.4% triple negative. 82% had polio antibodies type 1, 85% antibodies type 2 and 76% antibodies type 3. At the start of the trial 54% of the vaccinees excreted enteroviruses. Only in 12% young infants had enterovirus in anal swabs and seroconverted well. In view of the prevalence of paralytic poliomyelitis in tiny babies an early oral polio immunisation in the tropics is highly recommended.
Antibodies, Viral↗
[Naturally acquired tetanus antitoxin in the serum of children and adults in Mali].
Among 48 adults without a history of tetanus immunization, we found with the aid of indirect hemagglutination test 20 individuals with protective tetanus antibody titers, 23 with low levels of antitoxin (under 0,1 I.U./ml) and 5 devoid of tetanus antitoxin. In two blood samples of 99 unvaccinated children under 3 years of age (taken at 7 months intervall) 12,1% showed tetanus antitoxin in the first serum sample and 16,2% in the second sample. Protective antibody titers could be found only in 4 children in each of the first and second serum sample. The data suggest a silent oral immunization by tetanus bacilli thus boosting under unhygienic conditions the tetanus immunity with advancing age.
Adult↗
[Significance of the presence of Australia antigen in liver diseases seen in a department of internal medicine in Abidjan].
The exact responsibility of the hepatitis B virus in hepatic diseases seen in Ivory Coast is difficult to specify for several reasons, particularly technical ones. Nevertheless, we have tried to determine the prevalence of the HB virus in hospital practice and in patients hospitalized for liver diseases (viral hepatitis, cirrhosis, primary liver cancer). Comparison of the results to the prevalence of the virus in the ivorian population and statistical processing has led us to moderate the influence of HB virus in the different hepatic disorders. In primary liver cancer, the role of aflatoxine whose carcinogenic potential is now well established has not been disproved.
Adult↗
[Ectopic pheochromocytoma in black Africans : rule or exception? Apropos of a case of recurrent ectopic pheochromocytoma].
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Adolescent↗
[Differences in rubella immunity in Mali and Hamburg and their consequences].
The rare occurrence of rubella embryopathy in Mali stimulated us to investigate the rubella immunity of the population. Sera from females from Hamburg (n = 97) between 16 and 42 years old were in 84,5% seropositive (hemolysin-in-gel test) whilst a sample of Malien females (n = 99) were positive in 92,9%. Our investigations showed that the Malien children were significantly (p = less than 0.001) earlier infected by rubella than in Hamburg (Mali: children under 8 years [n = 196] in 46.9%; Hamburg [n = 151] in 20.5%). In Mali 7-8 years old children were already in 87.5% seropositive (Hamburg: only in 46.7%). The early immunity in childhood is due to the bigger African family in comparison with the smaller European family. The height of rubella serum titers was in grown-ups identical, but the relationship was vice versa in both studied newborn populations. Newborns from Mali showed lower rubella antibody titers than their mothers (newborns from Hamburg had a tendency to higher titers). Similar relationships were found already in the amount of neutralizing polioantibodies in newborns from both countries. A rubella immunisation in Mali seems not to be indicated.
Adolescent↗
Natural antibody response to Plasmodium falciparum Exp-1, MSP-3 and GLURP long synthetic peptides and association with protection.
A longitudinal study was undertaken in Burkina Faso among 293 children aged 6 months to 9 years in order to determine the correlation between an antibody response to several individual malarial antigens and malarial infection. It was found that the presence of a positive antibody response at the beginning of the rainy season to three long synthetic peptides corresponding to Plasmodium falciparum Exp-1 101-162, MSP-3 154-249 and GLURP 801-920 but not to CSP 274-375 correlated with a statistically significant decrease in malarial infection during the ongoing transmission season. The simultaneous presence of an antibody response to more than one antigen is indicative of a lower frequency of malarial infection. This gives scientific credibility to the notion that a successful malaria vaccine should contain multiple antigens.
Animals↗
[Maternal risk factors and low birth weight in Senegalese teenagers: the example of a hospital centre in Dakar].
AIMS OF THE STUDY: a) to identify the risk factors associated with newborn babies' low birth weight in teenage mothers; b) to propose prevention strategies for lower-ing neonatal morbidity and mortality. SPHERE OF THE STUDY: the study was carried out at the maternity and neonatology service of the Abass Ndao hospital centre, a urban community hospital located in the Southern part of Dakar. MATIERIAL AND METHODS: this retrospective study was carried out between July 1, 1998 and June 31, 1999. All new mothers under 20 who had given birth to living newborn babies have been included in the study and categorised into two groups, according to their babies' birth weight: 1) a first group of teenagers whose newborn babies' birth weight was lower than 2,500 g (low birth weight); 2) a second group constituted of women whose newborn babies' birth weight was higher than 2,500 g, and which was used as a control. The socio-demographic, biometrics, maternal and obstetric factors have been analysed and compared. RESULTS: out of the 4,586 women in childbirth during the study period, 456 were under 20 years of age, which corresponds to a prevalence rate of 10%. One hundred and five women had newborns weighing less than 2,500 g, which corresponds to a prevalence rate of 23%. Certain factors were found to be significantly associated with low birth weight: low weight gain during pregnancy (p = 0.04), fewer antenatal consultations (0.006), and kidney-related syndromes during pregnancy (0.0005). CONCLUSION: The results of that study allow us to recommend the following strategies: - control and improvement of nutritional behaviour during pregnancy; campaigning for a better attendance at antenatal consultation services for the early detection of pathologies during pregnancy and for preventing kidney-related syndromes.
Adolescent↗
[Epidemiology of infections caused by human immunodeficiency viruses HIV-1 and HIV-2 in the Ivory Coast].
A study of antibodies to HIV1 and HIV2 has been performed among selected groups in Ivory Coast from January to December 1987. In total, 2,578 serum samples were examined. A seropositivity to HIV1 and/or HIV2 was observed in 32 (2.4%) of 1.334 healthy subjects of the general population from 5 different areas, 9 (3.6%) of 246 pregnant women, 58 (12.3%) of 471 blood donors, 72 (34.3%) of 210 female prostitutes, 23 (35.3%) of 65 patients with sexual transmitted diseases, 21 (35.6%) patients with chronic renal insufficiency and 98 (50.7%) patients with severe pulmonary tuberculosis. Among the 313 HIV antibodies carriers, the frequency of HIV1 infection (6.7%) was higher than HIV2 infection (2%). However, 3.4% had a double seropositivity HIV1 and HIV2.
Acquired Immunodeficiency Syndrome↗
[Epidemiological aspects of poliomyelitis in Mali (author's transl)].
1800 cases of poliomyelitis has been observed in Mali during 8 years from 1968 to 1975. Children, and specially infants from 6 months to 2 years are specially concerned with a sex-ratio giving a higher frequency in boys though this difference goes decreasing with age. The dry season and the hotter one are the two periods of great morbidity. The three types (I, II, III) have the same importance. Oral immunization at the age of 3 or 4 months must be extended.
Age Factors↗
[Mali children antipoliomyelitic immunity before and after two oral immunizations against poliomyelitis (author's transl)].
In tropical areas transport and storage of living antipoliomyelitic vaccine are difficult and consequently it is considered as hazardous to get a correct immunity with this vaccine. Still, good results have been obtained in Mali children with Sabin vaccine. A previous virological survey has shown that 31 p. 100 of children below 3 years carry enterovirus which are, for 30 p. 100 of them, wild poliovirus. In a serological survey conducted during the same period, near 50 p. 100 of the children in that age group were seronegative for the 3 types of virus and 90 p. 100 of the children between 4 to 7 had neutralizing antibodies against type I, 88 p. 100 against type II and 67 p. 100 against type III. By doubling or trebling the immunizing dose at the first vaccination, the following results have been observed after the second vaccination: 86 p. 100 of the immunized children under 3 years had neutralizing antipoliomyelitic antibodies (titre 1/10) against type I and II and 64 p. 100 against type III, whereas, in the elder group (from 4 to 7) the conversion rate is 100 p. 100 for types I and II and 96 p. 100 for type III.
Antibodies, Viral↗
[Leukocyte count in French people living in Mali].
The authors studied the leucocytes count of 173 French people living in Mali (West Africa) during 4 years. 8.3% of these subjects presented neutropenia under 1,800/mm3, 12.2% had lymphocytosis over 4,000/mm3 and 11.6% hypereosinophilia over 500/mm3. These abnormalities differ considerably from one year to another in the same subject; their frequency does not depend upon the age, the sex, the duration of the stay in Africa. Eosinophilia is secondary to helminthiasis. Neutropenia and lymphocytosis are probably secondary to unknown evironmental factors.
Adult↗