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Biomedical subjects

D Dreval

Publications and source records attributed to D Dreval.

7 recordsLinked to original sources
PubMed1996

O2 consumption in the in-vitro fetal side human placenta.

The relative dependence of placental O2 consumption (MO2) on O2 supply (SupO2) parameters, and the fraction of aerobic O2 utilization, was studied by in-vitro perfusion of the fetal side of term human placental lobes. Placental MO2 was a function of the combined effect of SupO2 parameters (PO2, perfusate flow rate, perfusate effective O2 solubility) and not of each separately. At SupO2 greater than 800 microliters/(min.lobe), MO2 saturated at 260 microliters/(min.lobe). No accumulation of O2 debt could be detected even after 2 h anoxia. Adding CN- or CO to perfusate did not abolish MO2, and a residual MO2 of 31-37% of control MO2 was measured. In its MO2, the placenta is a typical conformer tissue. This conformity enables conservation of O2 transfer to the embryo even when placental SupO2 is radically reduced. Only about 60-70% of placental MO2 is utilized in the aerobic respiratory pathway, while about 30-40% of the oxygen is used in other pathways.

Biological Availability↗
PubMed1994

Ureteric stent in severe hydronephrosis of pregnancy.

Eleven women (12 pregnancies) were included in the study. A double-pigtail ureteric stent was passed under cytoscopic vision in 8 patients. The mean gestational age on insertion of the stents was 29 weeks (range, 25-35 weeks). Delivery took place at a mean of 39 weeks (range, 35-41 weeks). Stents remained in situ for a mean of 9 weeks (range, 6-14 weeks) before delivery and were removed 4-5 weeks postpartum. Double pigtail ureteric stents did not expose the women to infection. Renal function tests remained within the normal limits. Ureteric stent is an effective method for internal drainage of severe hydronephrosis during pregnancy.

Adult↗
PubMed1994

Carnitine palmitoyl transferase deficiency in pregnancy--a case report.

Carnitine palmitoyl transferase deficiency is one of the mitochondrial myopathies characterized by weakness, exercise intolerance, and myoglobinuria after prolonged exercise. This is the first case report concerning a pregnant woman with carnitine palmitoyl transferase deficiency that was also proved by the decrease of carnitine palmitoyl transferase activity in uterine myometrium biopsy.

Adult↗
PubMed1989

Management of tubal pregnancy with methotrexate.

Ten women with tubal ectopic pregnancy were treated by the injection of methotrexate into the gestational sac under direct laparoscopic vision followed by a course of intramuscular therapy including folinic acid rescue. One course of treatment induced resolution of the extrauterine pregnancy in eight women. Complete resolution (beta-hCG less than 10 miu/ml) was achieved within 6-47 days (mean 14.5 days). Serum beta-hCG levels started to decline 3.4 days from the beginning of therapy. Length of hospital stay was 5-11 days (mean 6.4 days). Treatment failed in two patients. One woman had a laparoscopic tubal clip sterilization concomitantly with methotrexate treatment. Tubal patency was demonstrated in all the other seven women (100%) tested subsequently. There is a need to establish criteria for patient selection before methotrexate becomes a routine treatment for tubal pregnancy.

Adult↗
PubMed1988

Puerperal adynamic ileus.

Puerperal adynamic ileus includes acute mild and severe clinical manifestations. Acute severe puerperal adynamic ileus may constitute the clinical indication of a serious underlying disease, such as sepsis, rupture of uterus, intra-abdominal or retroperitoneal bleeding, ureteral pathology, intra-abdominal foreign body and internal diseases. Sometimes the diagnosis requires abdominal and chest X-ray, uterine exploration and intravenous pyelography. Surgical treatment requires proper previous general evaluation; and fluids, electrolytes and plasma should be provided.

Adult↗
PubMed1986

Management and outcome of vertex-breech and vertex-vertex presentation in twin gestation: a comparative study.

A comparative study of twin pregnancies with vertex-breech and vertex-vertex presentation was undertaken to evaluate the effect of mode of delivery on perinatal outcome. During the years 1978-1984 there were 89 cases of vertex-breech deliveries at our institution and a control group of 89 cases of vertex-vertex presentation were chosen. The cesarean section rate was 11.2% for both twins in vertex-breech, and 20.2% for the first twin and 23.6% for the second in vertex-vertex presentation. The primary indications for cesarean section were not related to the type of presentation. The perinatal mortality was 22.4/1000 in the study group and 89.8/1000 in the control population. There were no statistically significant differences in 5-min Apgar scores and perinatal morbidity between the two types of presentation. We found that the high perinatal morbidity and mortality of both twins is related to prematurity and intrauterine growth retardation and not associated with the type of presentation of the second twin. Therefore, routine cesarean section for vertex-breech presentation is not necessarily indicated.

Apgar Score↗