PubMed Health⌕ Search

Biomedical subjects

D Drown

Publications and source records attributed to D Drown.

5 recordsLinked to original sources
PubMed1993

Exploratory data analysis of hyperlipidemia on the Macintosh: software tools for analysis of biochemical, clinical, and genetic variables in 1677 consecutive lipid clinic patients.

Exploratory data analysis (EDA) software facilitates unstructured, iterative open exploration of complex datasets with the aid of multiple linked graphical displays. We are investigating relationships between plasma lipoproteins and coronary artery disease by retrospective analysis of 1677 consecutive UCSF Lipid Clinic patients. Our preliminary experience is with Data Deck 3.0 although several additional software programs (JMP 2.0, Systat 5.1, Minitab 8.0, StatView 4.0) are mentioned. Lipid diagnosis (751 women and 925 men) was 22% primary hypercholesterolemia, 19% combined hyperlipidemia, 3% dysbetalipoproteinemia, 15% endogenous lipemia, 4% mixed lipemia, 5% elevated Lp(a) and 32% with no major lipid abnormality. We found the Macintosh platform (68030) to be flexible and powerful for analysis of moderate size (less than 1 Mb) clinical datasets. High resolution color monitors (1024 x 768 pixels), fast hard disks (< 18 msec) and moderate amounts of system memory (8 + Mb) facilitate exploratory analysis.

Artificial Intelligence↗
PubMed1993

Prevention and control of chemical exposures in the rubber manufacturing industry in The Netherlands.

In a survey in the rubber manufacturing industry in The Netherlands both the chemical and physical exposure of operators as well as company policies on working conditions were assessed. Defining the effectiveness of control measures was a part of this study and is the subject of this article. A method of solution-directed workplace analysis was applied to compare and evaluate the control measures within this branch of industry. Elimination of sources appears to be a strategy for prevention which has been adopted on only a limited scale. Control of exposure to particulates is more frequently applied, with local exhaust ventilation as the most important control measure. Both qualitative and quantitative analysis confirmed that local exhaust ventilation has a limited effect. Dust-free forms of chemicals, especially those with health risks, are used on only a moderate scale. In addition to hazard identification and evaluation based on exposure levels, the foreseeable risks associated with the design and requirements of production processes were established. The forthcoming industrial agreement for the rubber manufacturing industry in The Netherlands will, amongst other measures, stimulate use of source related strategies.

Environmental Monitoring↗
PubMed1986

On causality, responsibility, and self-blame: a theoretical note.

Examples from the literature on "self-blame" for illness (Tennen, Affleck, & Gershman, 1986) and criminal victimization (Janoff-Bulman, 1979) illustrate insufficient attention to construct validity in the measurement of causality, responsibility, and blameworthiness. Distinctions among these terms have been drawn in detail in a recent theory of the attribution of blame (Shaver, 1985), and these are briefly described. We argue that in future research and theory in the attribution of responsibility and blame, especially self-blame, investigators should attend more carefully to such conceptual distinctions.

Adaptation, Psychological↗