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Biomedical subjects

D Ducournau

Publications and source records attributed to D Ducournau.

17 recordsLinked to original sources

[N-acetyl-aspartylglutamic acid eye drops in allergic-type conjuctivitis. Double-blind comparative clinical study].

Fifty patients with allergic conjunctivitis were included in a double-blind randomized clinical trial designed to compare the efficiency and tolerance of two antiallergic eye-drops: one containing NAAGA (22 patients), the other one containing disodium Cromoglycate (28 patients). Both treatments were used at a dosage of 1 drop 4 times per day. Ocular symptoms, conjunctivo-corneal signs and the subjective ocular condition assessed by the patients themselves with visual analogue scales, were all significantly improved by both eye-drops during the first month of treatment. Statistical analysis showed that patient ocular condition improved more rapidly with NAAGA eye-drops. In 25 patients (12 in the NAAGA group and 13 in the Cromoglycate group), the study was continued for an additional month according to a cross-over protocol. During the 2nd month of treatment, additional improvement of ocular symptoms and signs were observed with both eye-drops but more markedly in those patients who received NAAGA after Cromoglycate. Ocular tolerance was good for both eye-drops.

Adolescent

[Systematisation of the choroïdal vasculature (author's transl)].

The systematization of the choroïdal vasculature has been studied by injection of radio-opaque material. The most important points are:--the absence of specific macular arteries,--the presence of two different clusters of short posterior ciliary arteries: a para-optic cluster and a remote cluster,--the inconstant presence of anterior recurrent ciliary arteries,--the absence of anastomoses between the S.P.C.A. arteries,--the segmental distribution of the capillaries,--the lobules are autonomous, but non independent,--the greatest variability of that systematization.

Animals

[Value of perforating keratoplasty in the treatment of chronic oedemas of the cornea (author's transl)].

A total of 75 cases of chronic diffuse or central oedemas of the cornea were treated, and the modern techniques of perforating keratoplasty used gave 68% of good anatomical results for all the various etiologies taken together. Prognosis varies according to whether there is one or many etiological factors. In "simple" cases with a single etiopathogenic mechanism, 88% of good anatomical results were obtained and the patient has a 50% chance of recuperating visual acuity from 5 to 10/10 Pa2. In "complex" cases, or when surgical treatment of the oedema had been previously attempted, only 30% of good anatomical results were obtained and there is a 60% chance of not helping the patient in any way.

Chronic Disease