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D E Logie

Publications and source records attributed to D E Logie.

10 recordsLinked to original sources

Reframing the HIV/AIDS debate in developing countries III: an effective, equitable response.

Developing countries need to balance resources for treatment and prevention. In Southern Africa, only 100,000 out of 4.1 million people who need HIV/AIDS anti-retroviral therapy (ART) are able to access it. The drop in the price of ART has led to opportunities to increase the numbers receiving treatment, but problems remain. Increasing health service focus on HIV might poach staff and resource from other important programs like TB, malaria or child health. It depends on good organisation and laboratory support. It may medicalise the epidemic and distract attention from the need for education and prevention. There is now good evidence that preventive strategies, including STD treatment, improved practices of blood transfusion and needle use, use of drugs to prevent mother child transmission, voluntary counselling and testing, increased condom availability and behaviour change are very effective in reducing spread. It is obvious that both treatment and prevention strategies are necessary. International aid is still inadequate. The European Union spends 50 billion dollars on agricultural subsidies, but donates only 140 million dollars for HIV in Africa. As funding increases, it is vital that it is well used and reaches the people who need it most.

Journal Article↗

Plasma immunoglobulin concentrations in mothers and newborn children with special reference to placental malaria: Studies in the Gambia, Nigeria, and Switzerland.

The immunoglobulin levels in sera from mothers and newborn infants were studied in Gambian, Nigerian, and Swiss populations. The maternal levels of IgG and IgM, but not IgA, varied with locality. As they were highest in Gambian and lowest in Swiss women, they may have reflected differences in the endemicity of infectious diseases in the different environments. The neonatal Ig levels showed less variation than the maternal. Neither maternal nor neonatal levels of IgG showed any consistent relationship with birthweight; however, when maternal IgG levels were low the neonatal levels tended to exceed them. The mean IgG and IgM levels were higher in Gambian than in Nigerian or Swiss infants; the higher IgM values may have been due to more frequent antigenic stimulation in utero in the Gambian group. Evidence of placental malaria, mainly falciparum, was found in 76 of 234 Gambian women. No parasites were found in the blood from any neonate. The maternal levels of IgG, but not of IgM or IgA, were significantly elevated in association with placental malaria. The neonatal immunoglobulin levels were not influenced by placental malaria and no evidence was found to indicate that malaria infection of the placenta induced an immune response in the fetus.

Birth Weight↗