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D E MacIntyre

Publications and source records attributed to D E MacIntyre.

103 records · Page 6Linked to original sources
PubMed1976

Platelet-aggregating activity of type I and type III collagens from human aorta and chicken skin.

Human or chicken type III collagen dissolved in 0.1 M-acetic acid was much more potent than type I collagen at inducing platelet aggregation. After incubation in 0.38M-Na2HPO4 to promote fibrillogenesis, the platelet-aggregating activity of both collagen types increased, and type I was then virtually equiactive with type III. Preincubation in cell-free plasma increased the activity of chicken but not that of human collagen. The platelet-aggregating activity of type III collagen did not appear to depend on the integrity of the intrachain disulphide bonds.

Adult↗