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Biomedical subjects

D E Maynard

Publications and source records attributed to D E Maynard.

8 recordsLinked to original sources

Intrapartum fetal monitoring with the cerebral function monitor.

We report a trial of the technical feasibility of monitoring the state of the fetal brain during labour using the Cerebral Function Monitor (CFM). This device was developed for long-term monitoring of the electroencephalogram (EEG). A tripolar scalp electrode allows removal of the fetal electrocardiograph (ECG) from the fetal EEG. Technically satisfactory recordings were obtained from 15 fetuses during labour for periods of up to 6 1/2 hours before delivery. There were alterations of CFM trace with fetal distress and also during general anesthesia for Caesarean section.

Anesthesia, General

EEG processing by the Cerebral Function Monitor (CFM).

The Cerebral Function Monitor (CFM) is a machine designed to monitor EEG over long periods of time from hours to several days. It produces on a slow speed chart recorder a write-out of a processed EEG signal in parallel with a continuous measurement of electrode impedance. A description is given of the way in which the CFM processes both EEG and electrode impedance information. Some CFM applications are mentioned.

Brain

Removal of EKG from fetal CFM recordings.

The monitoring of fetal EEG during labour can assist in identifying the effects on the fetus of anaesthetic and other drugs administered to the mother. Additionally it assists in detecting inadequate cerebral perfusion. One unsuccessful and one successful method are described of removing fetal EKG from the fetal EEG signal, so enabling the Cerebral Function Monitor to be used to monitor the fetal EEG. Examples of results are given.

Brain

Development of the CFM: the Cerebral Function Analysing Monitor (CFAM).

Use of the Cerebral Function Monitor (CFM) to monitor anaesthetic procedures has led to improvements of design. A standard CFM can be modified to enable it to be controlled by a microprocessor. An altered chart output format is produced which incorporates both frequency information and a better indication of trends. Alpha-numerical information can be given on a visual display unit. The extended instrument, of which preliminary details are given, is called the Cerebral Function Analysing Monitor (CFAM).

Anesthesiology

E.E.G. monitoring for the control of anaesthesia produced by the infusion of althesin in primates.

The continuous infusion of Althesin under electroencephalographic (e.e.g.) control provided a constant level of light anaesthesia for periods of 1--5.5 h during experimental brain hypoxia in spontaneously breathing baboons and Rhesus monkeys. Polygraphic records (respiration, heart rate, arterial pressure, cerebral venous sinus pressure, end-tidal gas concentrations) and also estimation of blood-gas tensions, pH, and concentrations of pyruvate and lactate demonstrated a steady physiological state. Various methods of e.e.g. monitoring were tested to establish an optimal assessment of depth of anaesthesia as a guide to the control of the rate of infusion of Althesin. A purpose-built modification of the Cerebral Function Monitor was found to give unequivocal recognition of changing depths of anaesthesia.

Alfaxalone Alfadolone Mixture