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Biomedical subjects

D E Mineau

Publications and source records attributed to D E Mineau.

10 recordsLinked to original sources

Transcatheter arterial embolization--major complications and their prevention.

A thorough account is given of the complications of embolization techniques in nonneurovascular areas, including hepatic infarction, renal and splenic abscess formation. Infarction of the urinary bladder, gallbladder, stomach, and bowel are discussed. Suggestions are offered to prevent complications from embolization where possible. Specific agents for embolization are detailed and their relative merits are compared; ethyl alcohol has recently gained popularity for treating esophageal varices and infarcting renal tumors. Care is advocated when using alcohol in the renal arteries; employing this agent is currently contraindicated in the celiac and mesenteric arteries. Coils and balloon systems are also described along with their potential complications.

Abscess↗

Clinical intra-arterial digital subtraction imaging. Use of small volumes of iodinated contrast material or carbon dioxide.

Forty patients were examined with intra-arterial digital subtraction angiography (DSA) using meglumine iothalamate (202 mg iodine/ml) or CO2 as a contrast medium. Diagnostic studies were obtained in all patients. The use of CO2 resulted in diagnostic examinations of the common femoral artery to the level of the trifurcation. The use of CO2 and low-iodine-content contrast material reduced the iodine dosage, and temporal bandpass filtration DSA permitted a lower entrance exposure than pulsed systems. It is concluded that intra-arterial DSA, using the techniques described in this paper, will become a more important and widely used procedure than it currently is.

Angiography↗

Experimental transcatheter splenectomy using absolute ethanol.

Since ethanol is known to be effective for transcatheter infarction of the kidney, the authors evaluated it as an agent for splenic ablation in swine and dogs. Infarction was successful in 7 of 9 pigs and 4 of 5 dogs. Controlled segmental infarction using flow-directed balloon catheters was attempted and was successful in 3 pigs and 2 dogs. The maximum blood ethanol level was 78 mg/100 ml, and by 15 minutes after injection it was less than or equal to 20 mg/100 ml. There was no evidence of pancreatic or hepatic injury at autopsy. The authors conclude that with careful catheter positioning, controlled total or partial infarction of the spleen can be safely performed with absolute ethanol without risk of abscess formation, pneumonia, or significant damage to other organs.

Animals↗

Uncontrollable postpartum bleeding: a new approach to hemostasis through angiographic arterial embolization.

A case of severe postpartum hemorrhage is reported. Three separate surgical procedures failed to reveal the source of bleeding, and standard surgical techniques, including bilateral ligation of the hypogastric arteries, were unsuccessful in producing hemostasis. However, angiography successfully identified the specific bleeding vessel, and transcatheter embolization with Gelfoam fragments quickly and effectively stopped the hemorrhage. The authors consider angiographic embolization to be an effective alternative approach to the control of pelvic hemorrhage and recommend that the technique be considered prior to surgical intervention.

Adult↗

Retroperitoneal lipoma in a child.

A case of retroperitoneal lipoma in a child is presented. A lucent retroperitoneal mass was seen displacing the kidney and ureter without intrinsic renal involvement.

Child, Preschool↗