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Biomedical subjects

D E Savar

Publications and source records attributed to D E Savar.

4 recordsLinked to original sources

High-dose radiation to the orbit. A cause of skin graft failure after exenteration.

Two patients had orbital exenteration for recurrent basal cell carcinoma after multiple courses of radiation to the orbit. Postoperatively, there was sloughing of skin graft from the bony surfaces that received the highest exposure to the radiation, presumably secondary to death of soft-tissue elements within the bone. Incidentally, epithelialization of these areas secondarily by granulation failed to occur. The result was permanent denuding of large areas of orbital bone.

Aged↗

Intraocular effects of lint particles from disposable drapes.

Fragments of lint from a disposable paper head drape were implanted into the anterior chamber of 9 rabbit eyes. Eyes were removed at varying intervals after implantations and sectioned for microscopic examination. A localized inflammatory response appeared as early as day 1 and increased in severity during the first 10 days. The reaction began to abate, however, by the 14th day. Control eyes with sham operations failed to show any such reaction. Daily monitoring for cell and flare reaction was negative in all eyes.

Animals↗

A new approach to ocular moisture chambers.

A new approach is presented to the problem of moisture chamber spectacles for the treatment of the dry eye. This moisture chamber relies on soft polyurethane sidewalls, form fitting and flanged to avoid pressure at right angles to the skin surface. The result is a comfortable moisture chamber which has been used successfully by an eight-year-old patient for nine months. This has allowed the child to return to school with best visual acuity (aphakic) without a single recurrence of corneal erosion.

Body Water↗