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Biomedical subjects

D E Tikhomirov

Publications and source records attributed to D E Tikhomirov.

2 recordsLinked to original sources

[Clinico-endoscopic and morphologic characteristics of patients with Campylobacter infection].

Bacteriological examination of feces of 120 patients with signs of acute gastroenterocolitis revealed C. jejuni infection in 19 (7 per cent) of them. There was a certain difference between the clinical course of C. jejuni infection and acute dysentery. The endoscopic examination of the large intestine in jejuni infection demonstrated acute hemorrhagic or catarrhal colitis and phenomena of acute exudative inflammation were found during histomorphological study. C. jejuni infection can be diagnosed on the basis of the clinico-epidemiological findings and the results of bacteriological examination of the patients' feces.

Adolescent↗

[Acute Campylobacter colitis].

Biopsies of colon mucous membrane obtained at colonofibroscopy of 16 adult patients with colon campylobacteriosis were studied. Acute diffuse colitis was found in all cases. Exudative inflammation with hemorrhagic component and microerosion formation was found up to day 10 of the disease. Catarrhal inflammation was observed from day 10-16 during the period of convalescence. Abundant infiltration of tunica propria with eosinophylic leucocytes is a peculiar feature of colon campylobacteriosis. This, together with a diffuse character of inflammation, makes a difference with Shigella colitis. Complete normalization of the mucosa does not occur within 16 days.

Acute Disease↗