Biomedical subjects
Publications and source records attributed to D E Vander Ploeg.
A 12-year-old girl was evaluated for a widespread eruption of Spitz nevi. Multiple Spitz nevi are rare, and this variant is exceedingly rare. The reported cases of eruptive nevi of all types are briefly reviewed. Very little is known regarding cause, natural history, or treatment. Cutaneous stimulation occurring in a genetically predisposed individual is the proposed essential causative factor in this disorder.
Following 4 weeks of treatment, 32 of 35 tioconazole treated patients (91.4%) and 29 of 34 miconazole treated patients (85.3%) achieved clinical and mycologic cures. At follow-up four weeks after completion of treatment, 29 of 31 tioconazole treated patients (93.5%) and 25 of 28 miconazole treated patients (89.3%) remained cured. There was no significant difference between clinical, mycologic or clinical plus mycologic response to the two medications. The 96.2% positive culture correlation in this study is attributed to the selection of multiple culture sites.
The case of a 45-year-old Latin American man, who presented to the Dermatology Clinic with a 6-month history of hyperkeratotic lesions confined to the palms and the palmar aspects of the digits of both hands, is discussed. Biopsy of these lesions revealed the classic histologic findings of mycosis fungoides. The clinical and histologic differential diagnosis of mycosis fungoides is considered.
Lupus vulgaris is uncommon in the United States and occasionally goes unrecognized for years before the diagnosis is made. A 65-year-old Mexican-American man with disseminated tuberculosis was discovered to have a large annular lesion of lupus vulgaris on his buttocks and thighs. The lesion had been present and slowly enlarging for twenty-eight years. The clinical and histologic features of primary inoculation tuberculosis and reinfection tuberculosis of the skin are reviewed.
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