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D Eisenblätter

Publications and source records attributed to D Eisenblätter.

13 recordsLinked to original sources

Community-based stroke incidence trends from the 1970s through the 1980s in East Germany.

BACKGROUND AND PURPOSE: Stroke mortality has declined in most industrialized countries, but incidence rates have increased in some populations while they remained stable or even decreased in others. This study reports stroke incidence trends in East Germany over the past decades. METHODS: Prospective community-based stroke registers were run in East Germany over two different time periods: 1972 through 1973 in the Berlin-Lichtenberg district and 1985 through 1988 in 14 districts in the central and southern part of the country. Stroke cases were collected and validated in a uniform way using both the World Health Organization (WHO) recommendations for community stroke registers and the guidelines of the WHO MONICA protocol. RESULTS: Annual age-adjusted incidence rates of first-ever strokes rose among men aged 25 to 64 years from 48.4 per 100,000 in 1972 through 1973 to 88.0 per 100,000 in 1985 through 1988 (P < .05); incidence rates remained unchanged among women in this age range (52.6 and 52.5 per 100,000, respectively). Age-specific incidence rates increased among men in all age groups up to 74 years. Rising stroke rates were also observed in women under 55 years and between the ages of 65 and 74 years, whereas in women aged 55 to 65 years incidence rates declined by more than a third (P < .05). During the period from 1985 through 1988, stroke rates did not change. CONCLUSIONS: An increase in stroke incidence was detected that can be associated with a deteriorating risk factor profile in the East German population and, in particular, with hypertension in men.

Adult↗

[Incidence and prognosis of stroke episodes in the East German population. Results from a stroke register 1985-1988].

OBJECTIVES: To determine the incidence rate of stroke, case-fatality within 28 days and diagnostic accuracy in stroke cases in the study population. METHODS: Prospective stroke register, including all cases of complete stroke which occurred during 1985-1988 in the population aged 25-64 and 25-74, of 14 districts in East Germany. Case-respectively finding, validation and uniform data collection were carried out by physicians trained to use the WHO-MONICA protocol. RESULTS: Annual age-standardized event rates were 113 per 100,000 for men and 68/100,000 for women aged 25-64, rates for first-ever stroke were 88/100,000 for men and 52/100,000 for women. For both sexes, incidence and event rates rose exponentially with increasing age. Before age 45 more women than men were affected. 34% of patients aged 25-64 had died by 28 days. Case-fatality in men and women aged 65-74 was higher than in those ten years younger (p < 0.01) and tended to be higher in women. 10% of patients aged 25-64 and 26% of those in the age of 65-74 were treated outside hospital. Before age 65, CT examination and angiography were done in only 18 and 20%, respectively; in elderly patients even less frequently. CONCLUSIONS: The findings suggest that since the 1970s there may have been an increase of stroke incidence in the population of Eastern Germany. The high case-fatality following stroke is confirmed. Evidently there are deficiencies in the medical care of elderly stroke patients.

Adult↗

[Development of serum cholesterol and frequency of hypercholesterolemia in children and adolescents: results of the Berlin-Pankow cohort study].

The age-related evolution of serum cholesterol has been studied in a cohort of 475 boys and girls born in 1964, living in Berlin-Pankow district; they have been followed up from age 13-14 to 20-21 (response rate after eight years: 66%). At age 13-14, mean total cholesterol was higher among boys (183 +/- 34 mg/dl) as well as among girls (187 +/- 33 mg/dl) as compared with those observed in other populations. About one third of the subjects at this age had values greater than 200 mn/dl. There was a marked decrease in mean total cholesterol around age 14 in both sexes, inversely related to the degree of sexual maturity. Between age 15 and 20 the serum cholesterol rose continuously. After puberty girls had higher mean values than boys. The evolution of serum cholesterol changes during adolescence should be taken into account when assessing preventive measures in children and young people.

Adolescent↗

Risk factors in the population of the GDR-MONICA Study (1983/84).

The GDR-MONICA project comprises 25 administratively defined areas with a population of nearly two million people aged 25-64. Data from the first random sample survey are reported here. The survey gathered information regarding risk factors, dietary behaviour, physical activity and psychosocial factors from 11,281 persons aged 25-64. The average risk factor levels were high in the population: The mean casual blood pressure was 140/88 mmHg and 138/86 mmHg for men and women respectively. In both sexes the mean total cholesterol level exceeded 6.1 mmol/L, and the mean body mass index (BMI) was just over 26.0. The study population consumed, on average, excessive amounts of energy, fat, alcohol, and sodium, and too few carbohydrates. Preliminary conclusions regarding unfavourable trends in risk factor levels have been drawn by comparing the present data with other recent reliable epidemiological studies.

Adult↗

Behavioural determinants of blood pressure in pre-adolescents.

The relationship between blood pressure and behavioural syndromes assessed by means of an "adjective test" was examined in a group of 467 pre-adolescents. Preliminary results suggest that certain specific behaviour characteristics can be identified in individuals with elevated blood pressure already in childhood and adolescence. Cluster analysis showed that subjects with higher blood pressure do not constitute a psychologically homogeneous group but can be classed into one of the following three subgroups: individuals with "High Academic Performance", "Dysthymic Behaviour" or "Behavioural Disturbances". The relationship between blood pressure and behavioural factors is not mediated by covariables such as social status, sexual maturity, body mass, smoking habits, etc.

Adolescent↗