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Biomedical subjects

D Enache

Publications and source records attributed to D Enache.

14 recordsLinked to original sources

[Beta-blockers in glaucoma].

The paper presents the main beta-blockers used in glaucoma therapy, the common international nomination and the commercial nominations of these therapeutical agents which have opened up new prospects in the medication of glaucoma. Some pharmacological properties of the beta-blockers are reviewed: the beta-adrenolytic strength, the pharmacodynamic properties, the pharmacokinetic effects, the action principle, the therapeutical effects and also the local and general side effects of the beta-blockers used in glaucoma therapy.

Adrenergic beta-Antagonists

[Melanosis oculi and malignant choroid melanoma].

The patient aged 75 years presents since her youth, in the left eye, ocular melanosis with abnormal pigmentation of the sclerotic, hyperpigmentation of the iris and abnormal pigmentation of the fundus oculi. Six months ago, she noticed that she is not able to see with this eye, and the fundus oculi examination emphasizes a malignant choroidal melanoma, with a fixed detachment of the retina. The authors show that the denomination Bourquin's benign ocular melanosis, under which the affection is known, is improper, as 10% of the cases of ocular melanosis degenerate into melanosarcomas. The term melanosis oculi is the most adequate one.

Aged

[The extraction of the crystalline lens with trabeculectomy in open-angle glaucoma].

Trabeculectomy with the extraction of the crystalline in a single operating tempo, represents a progress in the solving of two affections through a single intervention. Of the total of 101 cases of open-angle glaucoma operated and analysed on 21 patients, trabeculectomy was practised in the extraction of the crystalline (21%). The ocular tension before the operation was between 21-30 mm Hg, on 15 patients, 31-40 mm Hg, on 4 patients and over 41 mm Hg on 2 patients. As to the visual acuity, it was below 1/50, due to the opacity of the crystalline and the advanced stage of the glaucoma. The technicality varied, according to the operator--either classical Cairns trabeculectomy, or Franimopoulos-protected trepano-trabeculectomy followed by the extraction of the intracapsulated crystalline. Small postoperation hemorrhages appeared in 6 of the cases observed in the anterior chamber and 4 small hemorrhages in the vitreous body were resorbed in 7-10 days. In all cases under observation, the postoperative ocular tension kept within 11 to 17 mm Hg. The extraction of the crystalline with trabeculectomy in open-angle glaucoma is easily performed and complications are not more frequent than in the simple extraction of the crystalline.

Aged

[Ocular lesions produced by the sting of Hymenoptera].

The author reports on two clinical cases and discusses the possible pathogenic mechanisms of the ocular manifestations induced by Hymenoptera bites in the eye and around the eye. The ocular manifestations are polymorphous both clinically and pathogenically. The appearance of cornea manifestations following bites in the periocular region suggest a possible elective localization of the symptomatology. Various mechanisms may be involved: direct traumatic, toxic, allergic and certain local predisposing tissular factors.

Adult