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Biomedical subjects

D Engelke

Publications and source records attributed to D Engelke.

At least 19 recordsLinked to original sources

[The importance of electromagnetic articulography in studying tongue motor function in the framework of an orthodontic diagnosis].

Objective data are required for assessing the influence of movements of the tongue on the position of the teeth. Electromagnetic articulography (EMA) makes it possible to track movements of the tongue using the principle of inductive distance measurement. A helmet made of light but robust acrylic material serves as a carrier for three transmitter coils; these latter are located in front of the forehead, in front of the chin, and at the back of the neck. Receiver coils are fixed to the tip of the tongue and at various points on the dorsum of the tongue. The distance between the receiver coils and the transmitter coils is calculated in real time by means of a personal computer. The movement trajectories are displayed on the computer screen in different colors in X-Y coordinates. The movements of the tongue are recorded in patients with correctly positioned front teeth and compared with those in patients with a frontal open bite. The significance of electromagnetic articulography for dental research and functional treatment is demonstrated.

Adolescent

[The follow-up of the orthodontic treatment of facial cleft patients with the Göttingen computer-supported documentation system].

The care of patients with cleft lip, alveolus, and palate demands supervision of the development and progress over a long period of time. It also requires a standardized and systematic basic documentation. In our cleft center the documentation is summarized on one sheet of paper with DIN-A4 formation (297 x 210 mm). The use of electronic data processing improves the documentation. The storage of general and medical data has been supplemented by a personal computer system, PC-System. Five years after developing of this computer aided documentation system several patients are shown as examples for the application of this system for longterm control patients with cleft lip, alveolus, and palate.

Child

Application of the condylar positioning appliance in mandibular sagittal split osteotomies with rigid skeletal fixation.

During orthodontic-surgical treatment of dentofacial deformities, centric relation of the mandibular condylar head to the fossa articularis must be maintained. Intraoperative application of the condylar positioning appliance, in combination with different surgical splints, allows three-dimensional adjustment of the jaw segments. The condylar positioning appliance can be used in osteotomies of the mandible alone, in isolated Le Fort I osteotomies, or in simultaneous osteotomies of the maxilla and mandible.

Bone Plates

[Changes in opening mobility due to surgical advancement of the mandible].

A prospective follow-up study of 21 class-II patients, who were treated with a combination of orthodontics and orthognathic surgery, revealed typical postoperative changes in opening mobility. Their characteristics were: a strong initial loss of mobility and a regeneration period of about one year. Because the increase of mobility could not completely compensate for the initial reduction, a significantly reduced mobility was detected 25.5 months postoperatively. This reduction was considered as clinically acceptable, since former studies showed more unfavorable developments. However, individual changes of mobility are worth of notice. The comparison of condylar-related axiographic measurements with incisal measurements showed that the reduction of the length of axiographic tracings was more prominent than the "clinical-effective" reduction of the combined condylar rotation and translation.

Adult

Positioning control of the upper incisors in orthognathic surgery. Pre-operative planning with the Model Positioning Device and intra-operative application of the Sandwich Splint.

In orthognathic surgery a three-dimensional positioning of the maxilla is possible by means of the Le Fort I osteotomy and subsequent maxillary movement. In treatment planning and at the time of surgery it is very important to achieve an exact positioning of the upper incisors in relation to the upper lip and the rest of the skull. The Model Positioning Device described here allows three-dimensional positioning of the upper incisors in one- or two-jaw surgery. The reference plane is the upper surface of the upper part of a semi-individually adjustable articulator. The application of the Sandwich Splint enables the three-dimensional positioning of the maxilla in relation to the rest of the skull. The Sandwich Splint ensures that the vertical position of the mandible in relation to the rest of the skull above the osteotomy plane is exactly reproducible in the pre- and post-operative situation in both model surgery and at time of surgery. To this mandibular position the maxilla is positioned in three dimensions, as preplanned. The vertical dimension, which is identically reproducible before and after surgery is measured with a caliper. After surgery the mandible can be rotated into the planned new intercuspidation.

Calibration

[Anaesthesia and spontaneous return of sensation following resection of the mandibular continuity with primary alloplastic materials].

Resection affecting the continuity of the mandible and the mandible nerve leads to complete anaesthesia of the lower lip and mental area, furthermore to deformity and functional disturbance like uncontrolled salivation. In our long term follow up study on multimodal neurological investigation sensibility is reported to have uncomplete regenerated spontaneously often already after one year. Complete sensory, however, could not be found; the incomplete sensory return was to be measured in individually different degrees of hypaesthesia. Furthermore the axonal qualities of the mandible nerve show different regenerative potential: the receptor function for pressure and contact sensitivity could be demonstrated in the most of cases, whereas the heat- and painreceptor qualities could not be revealed in all cases.

Adult

Control of vertical position of the maxilla in orthognathic surgery: clinical application of the sandwich splint.

The Le Fort I osteotomy can be used to change the position of the maxilla in all three dimensions. A presurgically fabricated occlusal splint is used to reproduce the planned sagittal and transverse position of the maxilla. Various methods for determining the proper vertical position have been described. The major difficulty in vertical control when these techniques are used is the sagittal change of the lower reference point as the maxilla is advanced. The relative error in the vertical plane increases with larger sagittal movements. The sandwich splint technique, with two stable intraoral reference points, can be used to ensure proper vertical positioning of the maxilla. This method enables exact measurement of the vertical dimension during cast surgery and in the operating room. Vertical measurements are based on the relationship between the mandible and skull base. This distance remains constant during splint fabrication and when the splint is used at surgery. Postoperatively, the mandible can be rotated into the new centric occlusion.

Dental Occlusion, Centric

Condylar position control during maxillary surgery: the condylar positioning appliance and three-dimensional double splint method.

A new method for positioning the maxilla and condyle after Le Fort I osteotomy maintains the patient's vertical dimension (ie, the relation of the mandible to the skull above the osteotomy plane) in the preoperative and postoperative positions during both cast surgery and actual surgery. During surgery the condylar positioning appliance is fixed to the anterolateral zygoma and the lateral cortex of the mandibular ramus bilaterally to orient the mandible in centric relation. The condylar positioning appliance is used with the three-dimensional double splint method. Two prefabricated splints enable three-dimensional positioning of the maxilla in the fixed mandibular position during surgery. Postoperatively, the mandible can be rotated into the new centric occlusion.

Centric Relation

[Clinical and instrumental examination of tongue motor function].

The examination of tongue motor functions requires a clinical examination of voluntary movements as well an objective evaluation of the intraoral movements during speech, deglutition, mastication and during rest. For a comparison with the simple visual assessment of voluntary movements with the mouth opened, intraoral tongue movements have been studied using various techniques. The use of lateral x-ray palatography and electromagnetic articulography (EMA) for objective intraoral measurement of tongue motor activitiesis described. Case examples are given for simultaneous recording of midsagittal movements of the tongue, the mandible and the velum during swallowing and speaking.

Deglutition

[Intraoral condyle-related positioning of the maxilla in Le Fort 1 osteotomies].

A new technique for positioning control in Le Fort I osteotomies is presented. This intraoral procedure allows three-dimensional positioning of the condyles in the desired centric or therapeutic relation and of the maxilla at the same time. It combines the intraoperative use of the "Condylar Positioning Appliance" with the "3D Doublesplint Method".

Dental Articulators

[Changes in axiographic patterns in orthodontic treatment. A comparison of findings in upper and lower early displacement pre- and two month post-operation].

It has been shown that electronic axiographic tracings of patients 2.5 months after a surgical advancement of the maxilla by Le-Fort-I osteotomie changed only slightly in comparison to preoperative tracings. The sagital opening path as well as the sagital protrusive path showed alterations in curvature. On the other hand sagital split osteotomie with consecutive advancement of the mandible influenced axiographic patterns profoundly. We found almost regularily shortenings of the tracings and often loss of curvature.

Humans

Effects of tRNA-intron structure on cleavage of precursor tRNAs by RNase P from Saccharomyces cerevisiae.

RNase P derived from S. cerevisiae nuclei was tested for its ability to cleave a variety of naturally occurring and selectively altered precursor-tRNA molecules to yield matured 5' termini. Precursors were synthesized in vitro in order to test which aspects of substrate structure are crucial to recognition and cleavage by RNase P. Base modifications in the precursor substrates are not required for cleavage by the enzyme, but deletion and substitution mutations affecting any portion of the precursor tertiary structure reduce cleavage. In particular, a number of alterations in the intervening sequence (IVS) reduce the susceptibility of the substrate to cleavage by RNase P. The significance of these results is discussed in reference to the contribution of the IVS to the structure of the precursor-tRNA.

DNA Mutational Analysis

[2 objective procedures for the assessment of motor functions after surgery of the tongue and velum].

Commonly, only radiographic procedures have been used up to now for the assessment of intraoral movements during swallowing, speech and voluntary motor activities. In this article two methods for assessing intraoral function without involving radiation exposure are described: palatography and electromagnetic articulography. Palatography is particularly useful as a screening procedure for the evaluation of certain lingual motor activities in patients who had undergone tumor surgery. Electromagnetic articulography (EMA) allows vector analyses of lingual and soft palate movements. Data of normal subjects, surgically treated cleft palate and tumor patients are demonstrated. Both methods are biologically safe and non-invasive and do not interfere to any significant degree with the functions to be analysed.

Deglutition

[Primary sulcoplasty with hydroxylapatite augmentation for extreme ridge resorption].

Hydroxylapatite is commonly used for augmentation of the atrophic alveolar ridge. A new surgical technique is described for HA-augmentation and simultaneous vestibuloplasty on the severely atrophic jaw. The open surgical technique includes a lingually based mucoperiostal flap, the implantation of Hydroxylapatite particles in a vicryl mesh and the use of a positioning splint. First results show a sufficient depth of the vestibular sulcus and only few complications (circumscripted mucosal erosions). No lateral or lingual dislocation of the implanted HA-particles and no permanent mental nerve anaesthesia were observed. The prosthodontic results show increased stability and retention of the dentures following the one stage surgery.

Aged